Lymphoid System pt.2 Flashcards

(51 cards)

1
Q

Lymph Node Follicles (2)

A
  1. Primary (unstimulated) follicles
  2. Secondary (stimulated) follicles
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2
Q

Lymph node follicles that are composed of small, dark, mature lymphocytes

A

Primary (unstimulated) follicles

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3
Q

Lymph node follicles that are composed of germinal center and mantle zone

A

Secondary (stimulated) follicles

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4
Q

Lighter-staining part of secondary (stimulated) follicles

A

Germinal center

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5
Q

Part of secondary (stimulated) follicles around germinal center; contains small, dark lymphocytes

A

Mantle zone

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6
Q

Part in the medulla of lymph node which contains B cells, plasma cells, and macrophages

A

Medullary cords

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7
Q

Part in the medulla of lymph node which contain reticular fibers, lymph, circulating cells, and antigens

A

Medullary sinuses

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8
Q

Parts of lymph node stroma which consist of dense irregular connective tissue (2)

A

Capsule and Trabeculae

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9
Q

Part of lymph node stroma which consists of reticular connective tissue (fibroblast & reticular fibers)

A

Fine stroma

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10
Q

Penetrate the capsule of lymph node on convex side which carry lymph (w/ antigen & cells) from sites of infection back to lymph nodes

A

Afferent Lymphatic Vessels

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11
Q

Leave through the hilum; carry lymph (w/ lymphocytes) from lymph node and return them to blood

A

Efferent Lymphatic Vessels

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12
Q

Depression on concave surface of lymph node

A

Hilum

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13
Q

Structures that enter the hilum of lymph node (2)

A
  1. Arteries
  2. Nerves
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14
Q

Structures that leave the hilum of lymph node (2)

A
  1. Veins
  2. Efferent lymphatics
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15
Q

Lymph flow through the node (7)

ASIM ELB

A
  1. Afferent Lymphatic
  2. Subcapsular Sinus
  3. Intermediate Sinus
  4. Medullary Sinus
  5. Efferent Lymphatics
  6. Larger lymphatics
  7. Blood
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16
Q

Venules with tall endothelial cells in paracortex; allow lymphocytes in blood vessels to adhere to endothelial cells and migrate across vessel wall to lymphoid tissue

A

High-endothelial venules

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17
Q

Move from blood circulation to lymphatic circulation via high-endothelial venules

A

Lymphocytes

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18
Q

Flow of Lymphocytes from blood to lymph in lymph node (5)

LACEL

A
  1. Lymph node in arterial vessels
  2. Arterioles
  3. Capillaries
  4. Endothelial cells of high-endothelial venules
  5. Lymphatic circulation in cortex
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19
Q

Lymphocytes from blood to lymph (6)

HACHLE

A
  1. Hilar arterioles
  2. Arterioles
  3. Capillaries
  4. High-endothelial venules
  5. Lymphatic circulation
  6. Efferent lymph vessels in hilum
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20
Q

Functions of Spleen (3)

A
  1. Immunologic filtration of blood - trapping of antigens
  2. Activation and proliferation of lymphocytes
  3. Removal of old or dead RBCs, platelets, and debris
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21
Q

Parenchyma of spleen is called ______ ____

22
Q

Splenic pulp consists of _____ ____ and ___ ____

A

white pulp & red pulp

23
Q

Color of red pulp

24
Q

Why is it called white pulp when it’s purple in color

A

because it’s made up of WBCs

25
Composition of white pulp (2)
1. Periarteriolar lymphatic sheaths (PALS) 2. Splenic Follicles (nodules)
26
Part of white pulp that is circular collections of T cells around arterioles
Periarteriolar lymphatic sheaths (PALS)
27
Like secondary follicles in lymph nodes, except with 1 more layer: marginal zone; composed of B cells; usually have arteriole at periphery
Splenic Follicles (nodules)
28
Spleen is composed of cortex and medulla. True or False?
False - spleen has no cortex nor medulla
29
3 Layers of Spleen
1. Germinal center 2. Mantle zone 3. Marginal zone
30
Layer of spleen with darker surroundings
Mantle zone
31
Layer of spleen with darker outside layer; contains arterioles (splenic artery)
Marginal zone
32
Part of spleen that consists of capsule, trabeculae, and reticular connective tissue
Stroma
33
Part of spleen that contains nerves, arteries, and veins
Hilum
34
Part of spleen that is the pathway of blood vessels
Trabeculae
35
Composition of red pulp (2)
1. Splenic sinuses (sinusoids) 2. Splenic cords (cords of Billroth)
36
Capillaries that are leaky vessels lined by specialized endothelial cells (stave cells) surrounded by rings of reticular fibers like hoops on a barrel; healthy RBCs easily squeeze thru here while old/damaged RBCs get stuck; found between the cords
Splenic sinuses (sinusoids)
37
Important for easy distribution of nutrients around; can be seen in organs that always need constant exchange of nutrients and gasses (e.g. spleen, liver)
Sinusoids
38
Located between sinuses; contain RBCs, granulocytes, lymphocytes, macrophages, platelets, and plasma cells
Splenic cords (cords of Billroth)
39
Type of circulation where walls have holes (plasma and other cellular components seep thru)
Open circulation
40
Type of circulation where walls have no holes (no cellular components will seep thru)
Close circulation
41
Lymphoid tissue in mucosa and submucosa of digestive, respiratory, reproductive, and urinary systems
Mucosa-Associated Lymphoid Tissue (MALT)
42
Examples of MALT
1. Tonsils 2. Peyer’s patches 3. Lymphoid tissue in oral mucosa
43
Aggregates of lymphoid follicles beneath the epithelium of the posterior oral cavity and nasopharynx; can produce toxins when infected
Tonsils
44
3 types of tonsils
1. Pharyngeal 2. Palatine 3. Lingual
45
1 tonsil in midline of nasopharynx; surface has gentle folds but no crypts; thin partial capsule along deep portion
Pharyngeal tonsil
46
Surface epithelium of pharyngeal tonsil
Pseudostratified ciliated columnar (sometimes w/ areas of stratified squamous)
47
2 tonsils in lateral oropharynx; 10-20 deep invaginations (sequestered crypts); thick partial capsule along deep portion
Palatine tonsil
48
Surface epithelium of palatine and lingual tonsil
Stratified squamous
49
Numerous small tonsils at base of tongue; each tonsil has 1 short crypt; no capsule; closely associated skeletal muscle and mucous salivary glands
Lingual tonsil
50
Made up of WBCs (phagocytes) which forms to digest foreign bodies in an infection
Pus
51
Once tonsils have pus, fever can only go down with the use of __________
antibiotic