Lymphoid System pt.2 Flashcards
(51 cards)
Lymph Node Follicles (2)
- Primary (unstimulated) follicles
- Secondary (stimulated) follicles
Lymph node follicles that are composed of small, dark, mature lymphocytes
Primary (unstimulated) follicles
Lymph node follicles that are composed of germinal center and mantle zone
Secondary (stimulated) follicles
Lighter-staining part of secondary (stimulated) follicles
Germinal center
Part of secondary (stimulated) follicles around germinal center; contains small, dark lymphocytes
Mantle zone
Part in the medulla of lymph node which contains B cells, plasma cells, and macrophages
Medullary cords
Part in the medulla of lymph node which contain reticular fibers, lymph, circulating cells, and antigens
Medullary sinuses
Parts of lymph node stroma which consist of dense irregular connective tissue (2)
Capsule and Trabeculae
Part of lymph node stroma which consists of reticular connective tissue (fibroblast & reticular fibers)
Fine stroma
Penetrate the capsule of lymph node on convex side which carry lymph (w/ antigen & cells) from sites of infection back to lymph nodes
Afferent Lymphatic Vessels
Leave through the hilum; carry lymph (w/ lymphocytes) from lymph node and return them to blood
Efferent Lymphatic Vessels
Depression on concave surface of lymph node
Hilum
Structures that enter the hilum of lymph node (2)
- Arteries
- Nerves
Structures that leave the hilum of lymph node (2)
- Veins
- Efferent lymphatics
Lymph flow through the node (7)
ASIM ELB
- Afferent Lymphatic
- Subcapsular Sinus
- Intermediate Sinus
- Medullary Sinus
- Efferent Lymphatics
- Larger lymphatics
- Blood
Venules with tall endothelial cells in paracortex; allow lymphocytes in blood vessels to adhere to endothelial cells and migrate across vessel wall to lymphoid tissue
High-endothelial venules
Move from blood circulation to lymphatic circulation via high-endothelial venules
Lymphocytes
Flow of Lymphocytes from blood to lymph in lymph node (5)
LACEL
- Lymph node in arterial vessels
- Arterioles
- Capillaries
- Endothelial cells of high-endothelial venules
- Lymphatic circulation in cortex
Lymphocytes from blood to lymph (6)
HACHLE
- Hilar arterioles
- Arterioles
- Capillaries
- High-endothelial venules
- Lymphatic circulation
- Efferent lymph vessels in hilum
Functions of Spleen (3)
- Immunologic filtration of blood - trapping of antigens
- Activation and proliferation of lymphocytes
- Removal of old or dead RBCs, platelets, and debris
Parenchyma of spleen is called ______ ____
splenic pulp
Splenic pulp consists of _____ ____ and ___ ____
white pulp & red pulp
Color of red pulp
Pink
Why is it called white pulp when it’s purple in color
because it’s made up of WBCs