Malaria Flashcards

(17 cards)

1
Q

causative agents of malaria, and their characteristics

A

P. falciparum: cerebral malaria
P. malariae: malaria in subtropics
P. vivax: persistent liver phase
P. ovale: west african

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2
Q

transmission of malaria

A

bit of an infected anopheles mosquito

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3
Q

life-cycle of malaria

A

-infected mosquito bites huma
-toxin travels to liver
-toxin invades hepatocytes in liver
-mosquito bites and picks up toxin

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4
Q

how to prevent getting malaria

A

-reduce exposure(mosquito nets and long sleeves)
-mosquito repellant
-insecticides
-chloriquine

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5
Q

critical issues related to treatment of malaria

A

strains may be multidrug resistant, relies on artesunate

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6
Q

why is malaria only in some locations

A

it follows where mosquitos go

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7
Q

how does human migration influence the spread of malaria

A

European exploration brought malaria to the Americas

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8
Q

what is the leading cause of disease in developing countries

A

malaria

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9
Q

“3 demons” of malaria

A

chills, fever, headache

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10
Q

malaria pathology symptoms

A

massive hemolysis
jaundice
black urine(“black water”)

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11
Q

what gave acacia trees the name “fever tree”

A

European explorers to Africa thought it caused diseases such as malaria

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12
Q

who was the first to view plasmodium sp. parasite under the microscope

A

Charles Laveran

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13
Q

what was malaria known as in British India

A

intermittent fever or ague

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14
Q

who discovered malaria protozoan in the stomach of anopheles mosquitos

A

Sir Ronald Ross

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15
Q

what stage of malaria does an infected mosquito inject when it bites

A

sporozoites

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16
Q

what plants are good at treating malaria

A

cinchona tree bark: quinine
wormwood plant: artemisinin

17
Q

what vaccine is there for malaria? what lifecycle form does it work on

A

R21 vaccine.
works on sporozoites