Flashcards in Male Urology Deck (155)
What type of tissue comprises 30% of the prostate?
What comprises the other 70%?
30%: Glandular tissue
What is the smallest structural component of glandular prostate?
T/F: Proliferation of the acini results in BPH
Proliferation of the ________ (Acini/Basement Membrane) of the prostate leads to prostate cancer
What are the three zones of the prostate?
Which zone of the prostate contains mucosal and submucosal glands?
Changes in this zone often lead to urethral pressure.
Which zone of the prostate contains the majority of prostatic glandular tissue and is the origin site for most adenocarcinomas of the prostate?
Which zone of the prostate is often described of as the "cone shaped" portion of the prostate?
T/F: The transitional zone of the prostate does NOT surround the urethra
It does surround the urethra
What percentage of men have BPH by the age of 60?
What is the mechanism for BPH development?
Testosterone is broken down by 5alpha-reductase to form DHT
DHT then binds to nuclear receptors in the prostate leading to BPH
What receptors in the prostate (near the bladder neck) result in smooth muscle contraction leading to LUTS associated with BPH?
What are examples of obstructive LUTS?
What are examples of irritative LUTS?
What are FOUR key components to a BPH work-up?
What 'imaging' study can be obtained to see if a patient is retaining urine?
PVR (Post-Void Residual)
What is the name of the 'imaging study' used to measure how strong a patient's urine stream is?
What is the name of the procedure used to visual the inside of the bladder?
What may the appearance of the bladder be described as if it has been squeezing hard against the prostate?
What medications used in BPH management "open up" the prostate through smooth muscle relaxation?
Non-Selective: Terazosin (Hytrin), Doxazosin
Selective: Tamsulosin (Flomax), Silodosin (Rapaflo)
What medications used in BPH management "shrink" the prostatic glands?
%-alpha reductase inhibitors.....
What is an antimuscarinic used in BPH management?
What are examples of surgical procedures used to manage BPH?
T/F: Recurrent UTIs attributable to BPH is NOT an indication for surgical management
It is an indication
T/F: Prostate CA is the 2nd leading cause of cancer death in US men
What are two crucial screening tools for prostate cancer?
What is the normal PSA range?
0.0 - 4.0
What are three examples of things that lead to a benign elevation in PSA?
T/F: You should always trend PSA values prior to jumping to conclusions or management decisions (ie: Biopsy)