Mar 25 neuroses Flashcards
(8 cards)
Schizophrenia:
Symptoms (DHELD):
Schizophrenia: Split Mind
Symptoms (DHELD):
D – Disturbed Thought Content
* Delusions (grandiose or persecutory)
* Loose associations (confused speech)
H – Hallucinations
* Hearing voices, seeing things that aren’t there
E – Emotional Disturbance
* Inappropriate laughter or flat affect (no emotions)
L – Loss of Functioning
* Neglect of hygiene, social withdrawal
D – Disturbed Behavior
* Agitation or catatonic stupor (lack of movement)
Theories of Schizophrenia (Genetic Contribution)
Highest risk in:
Genetic Contribution
Highest risk in:
* Identical twins, followed by children with two schizophrenic parents
Theories of Schizophrenia
The Dopamine Hypothesis (Slogan)
Evidence for excess dopamine: (3 things)
Theories of Schizophrenia
The Dopamine Hypothesis (Slogan):
* Drugs help the positive, not the negative.
Evidence for excess dopamine:
* Schizophrenia may involve excess dopamine activity in the brain
* Antipsychotic drugs reduce dopamine = lessen symptoms,
* Works best on positive symptoms (extra behaviors) and not on negative symptoms.
Theories of Schizophrenia (GENET):
G - Genetic Contribution:
E - Epigenetics
N - Neurodevelopmental Hypothesis:
E - Expressed Emotion
The Dopamine Hypothesis
Theories of Schizophrenia
The Dopamine Hypothesis
Early Idea:
Dopamine Receptors:
Antipsychotic Drugs:
Early Idea:
* Too much dopamine = schizophrenia
Dopamine Receptors:
* Too many D₂ receptors may play a role
Antipsychotic Drugs:
* Block D₂ receptors = reduce dopamine activity
Theories of Schizophrenia (Epigenetics): (2 things)
Epigenetics
* About 1 in 200 genes in psychotic patients show epigenetic changes
* Affects genes linked to neurotransmission and brain development
Theories of Schizophrenia (Neurodevelopmental Hypothesis): (2 things)
Neurodevelopmental Hypothesis
* Prenatal insults (e.g., viral infections, malnutrition, stress) disrupt brain development
* May lead to long-term vulnerability
Theories of Schizophrenia (Expressed Emotion (EE)):
Expressed Emotion (EE)
* Returning to highly critical or emotionally intense families increases risk of relaps