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Phar 714 > Marijuana > Flashcards

Marijuana Flashcards

1
Q

What chemical is contained in turmeric root?

A

Curcumin

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2
Q

What was synthesized from the willow tree? (Which acid)

What drug contains this?

A

Acetylsalicylic acid

Aspirin

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3
Q

What year was cannabis listed in U.S. pharmacopoeia and when was it removed?

A

1851

1941

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4
Q

What year was the marijuana tax act enacted?

A

1937

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5
Q

Where are cannabinoids found? (multiple answers)

a. Endocannabinoid system
b. Cannabis plant
c. Usually in diet supplements
d. Synthetic forms

A

a,b,d

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6
Q 
What year was marijuana regulated by DEA?
What class of controlled substance was it given?
A

1970

Schedule 1

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7
Q

What year did the Oregon medical marijuana act get approved and what did it do?

A

1998

Allowed medical use of marijuana in Oregon for debilitating conditions

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8
Q

What is OMMP?

A

Oregon medical marijuana program:

A state-controlled permit system for marijuana

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9
Q

When were medical marijuana dispensaries approved in Oregon?

A

Jan 2014

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10
Q

When did recreational marijuana become approved for legal sale in Oregon?

A

July 2015

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11
Q

What does OHA stand for

What do they do?

A

Oregon health authority

Regulate medical sales

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12
Q

What are the secondary metabolites found in marijuana? (Multiple answers)

a. Flavenoids
b. Tiotropines
c. Cannabinoids
d. Sesquiterpenes
e. Allinoids
f. Triterpenes
g. Lignans
h. Quadropenes
i. Monoterpenes

A

a,c,d,f,g,i

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13
Q

Which chemical in marijuana binds to both cannabinoid receptors (CB1 and CB2)?

A

THC

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14
Q

Does CBD bind to receptors? What does it do?

A

No, changes endogenous signals (changes shape of receptor changing the signals of receptor)

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15
Q

Legally speaking, agricultural hemp must contain less than what percentage of THC?

A

0.3%

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16
Q

T/F CB1 is the most abundant G-protein coupled receptor in the brain

A

True

17
Q

What is the cannabinoid potency profile

A

Testing of plant material to find % weight cannabinoids/total plant weight

18
Q

What medical conditions is CBD used for? (Multiple answers)

a. Narcolepsy
b. Cancer
c. Neurological conditions
d. OCD
e. Glaucoma
f. ADHD/ADD
g. HIV/AIDS
h. Pain, nausea, seizures, muscle spasms

A

b,c,e,g,h

19
Q

How has marijuana changed over time (potency)

A

Marijuana has become more potent over time - higher concentration of THC

20
Q

What is the main reason for use of medical marijuana?

A

For severe pain

21
Q

Why is marijuana useful for pain? (multiple answers)

a. it is considered an analgesic
b. it induces a sense of euphoria
c. cannabinoids control pain perception
d. Deactivates certain pain receptors in the brain

A

a,c

22
Q

Where in body are endogenous opioid and cannabinoid systems located? (multiple answers)

a. liver
b. brain
c. reproductive organs
d. spinal cord
e. periphery
f. stomach

A

b,d,e

23
Q

What drug is approved in other countries containing THC/CBD to help with multiple sclerosis/pain

A

Nabiximols (Satvex)

24
Q

Why is marijuana helpful for anorexia/wasting syndromes?

A

Increases appetite

25
Q

Names of 4 drugs FDA approved containing CBD

A

Nabilone
Dronabinol
Dronabinol liquid
Epidiolex

26
Q 
What are the adverse effects of marijuana? (multiple answers)
a. red eyes, dilation, blurred vision
b. increased heart rate
c. increased blood pressure
d. decreased blood pressure
e. decreased heart rate
f. dry mouth
g. hypoglycemia
h. hyperglycemia
i. drowsiness
j, impaired short term memory/ altered judgement
k. impaired motor coordination
l. abnormal breathing
A

a,b,d,f,i,j,k

27
Q

What risks are involved? (multiple answers)

a. addiction
b. use with pre-existing psychiatric illness
c. overdose: causing the heart to stop, can result in death
d. lung health
e. irreversible polyuria

A

a,b,d

28
Q

Should you use marijuana during pregnancy or lactation?

A

No

29
Q

Is it okay to combine marijuana with other drugs such as sedatives or anti-histamines?

A

No

30
Q

what is cannabinoid hyperemesis syndrome?

a. substantial memory loss due to an overly high intake of THC
b. nausea, vomiting, and abdominal pain due to long-term use of marijuana
c. a term used to describe the withdrawal symptoms of stopping the use of marijuana due to addiction
d. a rare condition that causes severe vomiting after smoking marijuana

A

b

31
Q

hemp extract became FDA-approved in what year?

A

2018

32
Q

T/F cannabidiol (CBD) binds to CB1 and CB2

A

False

33
Q

human cannabinoid receptors are primarily located:

a. in the cytoplasm
b. in the nucleus
c. outside the cell
d. on the plasma membrane

A

d

34
Q

medical use of marijuana to treat epilepsy in children is focused on:

a. mostly synthetic cannabis products not derived from plants
b. strains with high levels of cannabidiol (CBD)
c. strains with high levels of tetrahydrocannabinol (THC)
d. mostly marijuana extracts and concentrates

A

b

Phar 714 (10 decks)

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