Maternal Phys Flashcards
Osmoregulation in early pregnancy is altered via _______ secretion.
arginine vasopressin
Does serum sodium increase or decrease in pregnancy?
decrease (even tho Na+ is increased bc the water increases, too)
Is additional sodium retained or released in pregnancy?
retained
What mediates the decreased systemic vascular resistance in prego?
progesterone
Does preload increase or decrease in pregnancy? Why?
increase bc of increased venous return
Does afterload increase or decrease in pregnancy? Why?
decrease bc of decreased vascular resistance
Does end-diastolic volume increase or decrease in pregnancy? Why?
no change
Why are pregnant women susceptible to hemorrhoids, DVTs, edema, and varicose veins?
increases in venous pressure due to increased venous return
Why does cardiac output increase during labor?
pain
force of contraction pushes blood out of uterus into systemic circulation, increasing venous return –> increased preload –> increased cardiac output
Why is aortic stenosis a problem in pregnancy?
these pts have a fixed stroke volume
What effect can pre-existing HTN have on the fetus?
IUGR
What mediates the GFR and RPF changes in pregnancy?
NO and relaxin
On which side of the body is a DVT more likely to occur in pregnancy?
the left
What factors contribute to increased DVT risk in pregnancy?
increased stasis
increased coagulation factors
In pregnancy, protein C ______.
stays Constant
In pregnancy, protein S ______.
sinks
Which clotting factors increase in pregnancy?
1, 7, 8, 9, 10
Which clotting factors decrease in pregnancy?
11 and 13
What is the prophylactic tx for DVT in pregnancy?
LMW Heparin (Heparin keeps the baby Happy)
What does Warfarin/Coumadin do to a fetus?
nasal hypoplasia
stippling of bones
brachydactyly
What is Ptyalism?
increased saliva production
What causes decreased GI tone and mobility in prego?
progesterone
Why are prego females at an increased risk of developing peptic ulcer disease?
Increased gastric mucin
decreased gastric acid
enhanced immune tolerance to H. pylori
Why are prego females at an increased risk of developing gallstones?
fasting and residual volumes of GB are doubled
GB empties more slowly
Increased biliary cholesterol saturation with decreased
biliary chenodeoxycholic acid
