Placenta Flashcards

1
Q

blastocyst

A

an inner cell mass which subsequently forms the embryo + the outer layer( the trophoblast) surrounding the fluid-filled cavity known as the blastocoele

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2
Q

Collectively, this is an inner cell mass which subsequently forms the embryo + the outer layer( the trophoblast) surrounding the fluid-filled cavity known as the blastocoele.

A

blastocyst

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3
Q

chorionic villi

A

part of the border btw the maternal and fetal blood

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4
Q

These form part of the border btw the maternal and fetal blood.

A

chorionic villi

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5
Q

cotyledon

A

The maternal surface is divided by septa into cotyledons

Each cotyledon contains several main stem villi with many branching villi.

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6
Q

The maternal surface is divided by septa into ______;

each contains several main stem villi with many branching villi.

A

cotyledon

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7
Q

cytotrophoblast

A

the inner layer of the trophoblast; the stem cells; important for implantation

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8
Q

This is the inner layer of the trophoblast; the stem cells; important for implantation.

A

cytotrophoblast

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9
Q

decidua

A

the endometrium during pregnancy

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10
Q

This is the term for the endometrium during pregnancy.

A

decidua

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11
Q

diffusion-limited transport

A

cross the placenta slowly
depends on the rate of movement across the syncytiotrophoblast membranes
ex: oxygen

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12
Q

Substances subject to ______ cross the placenta relatively slowly. The rate-limiting step is the rate of movement across the syncytiotrophoblast membranes between the intervillous space and the fetal capillaries.

A

diffusion-limited transport

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13
Q

flow-limited transport

A

cross the placenta more rapidly

dependent on plasma concentration and the rate of blood flow

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14
Q

For substances that cross the placenta more rapidly, transport is dependent on plasma concentration and the rate of blood flow. This ______ can be affected by several factors, including changes in uterine blood flow and therefore placental perfusion.

A

flow-limited transport

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15
Q

human placental lactogen (hPL)

A

a counter-regulatory (anti-insulin) hormone

contributes to the increased insulin resistance seen in pregnancy and development of gestational diabetes

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16
Q

This is a counter-regulatory (anti-insulin) hormone that contributes to the increased insulin resistance seen in pregnancy and development of gestational diabetes.

A

human placental lactogen (hPL)

17
Q

intervillous space

A

the space between the villi containing the vessels of the mother and the embryo

18
Q

This is the space between the villi containing the vessels of the mother and the embryo.

A

intervillous space

19
Q

oligohydramnios

A

a subnormal volume of amniotic fluid

20
Q

This is a subnormal volume of amniotic fluid.

A

oligohydramnios

21
Q

polyhydramnios

A

a supernormal volume of amniotic fluid

22
Q

This is a supernormal volume of amniotic fluid.

A

polyhydramnios

23
Q

rupture of membranes

A

aka amniorrhexis

rupture of the amniotic sac

24
Q

Aka amniorrhexis, this is the rupture of the amniotic sac.

A

rupture of membranes

25
Q

syncytiotrophoblast

A

the epithelial covering of the highly vascular embryonic placental villi, which invades the wall of the uterus to establish nutrient circulation between the embryo and the mother

26
Q

This is the epithelial covering of the highly vascular embryonic placental villi, which invades the wall of the uterus to establish nutrient circulation between the embryo and the mother.

A

syncytiotrophoblast

27
Q

trophoblast

A

a layer of tissue on the outside of a mammalian blastula, supplying the embryo with nourishment and later forming the major part of the placenta

28
Q

This is a layer of tissue on the outside of a mammalian blastula, supplying the embryo with nourishment and later forming the major part of the placenta.

A

trophoblast

29
Q

Maternal blood comes in direct contact with ______.

A

fetal trophoblasts (but not fetal blood)

30
Q

Once the blastocyst attaches to the endometrium, the _______ proliferates.

A

trophectoderm

31
Q

A primary villus consists of a _______.

A

cytotrophoblast core surrounded by syncytiotrophoblasts

32
Q

Fetal hemoglobin (HbF) has different _____ chains than adult hemoglobin A (HbA).

A

beta-like

33
Q

The functional difference between HbF and HbA is that at any oxygen tension and pH fetal erythrocytes _____.

A

have a greater affinity for oxygen than adult erythrocytes

34
Q

Fetal erythrocytes have a lower concentration of ______ than maternal erythrocytes.

A

2,3-diphosphoglycerate (2,3-DPG)

35
Q

hCG is made by ______ cells and maintains the corpus luteum.

A

trophoblast

36
Q

_____ is made by trophoblast cells and maintains the corpus luteum.

A

hCG

37
Q

Since ____ is not transported across the placenta, any found in fetal blood has been produced by the fetus and may represent a response to a congenital infection.

A

IgM

38
Q

Transport of _____ to the Rh factor is what causes fetal immune hydrops in an Rh+ fetus in an isoimmunized Rh- mother.

A

IgG