Medication interactions

Question 1

What drugs interact with Ketamine

Answer 1

Sympathomimetics: Synergism

Question 2

What drugs interact with Ketorolac

Answer 2

Blood thinners, NSAIDs, SSRIs: Bleeding

Question 3

What drugs interact with Fentanyl

Answer 3

Naloxone: antagonist

Question 4

What drugs interact with Hydromorphone Hydrochloride

Answer 4

Naloxone: antagonist
TCAs, SSRIs: Serotonin syndrome

Question 5

What drugs interact with Morphine

Answer 5

Naloxone: antagonist
MAOIs, Alcohol: Increases levels

Question 6

What drugs interact with Midazolam

Answer 6

Alcohol, depressants: Respiratory depression

Question 7

What drugs interact with Lidocaine

Answer 7

Xanax, Metoprolol, cyclobenzaprine, duloxetine, lorazepam: Increase effects

Question 8

What drugs interact with Diazepam

Answer 8

Sedating agents, alcohol: Respiratory depression

Question 9

Droperidol

Answer 9

-Nitrates, Antihypertensives: Hypotension
-CNS depressants: Increased CNS depression

Question 10

What drugs interact with Ziprasidone

Answer 10

CNS depressants: Respiratory depression

Question 11

Lorazepam

Answer 11

CNS depressants: Respiratory depression

Question 12

What drugs interact with Epinephrine

Answer 12

-Inhibits effects: Alpha Adrenergic blocker, antihypertensive, vasodilators, diuretics
-Increases effects: Beta-Adrenergic blockers, MAO inhibitors, COMT inhibitors
-Sodium Bicarbonate: Do not mix in a line

Question 13

What drugs interact with Nitroglycerin

Answer 13

Beta Blockers, alcohol, Calcium Channel blockers, ED medications: Hypotension

Question 14

What drugs interact with Aspirin

Answer 14

Other NSAIDs: GI Upset
Blood Thinners: Increased Risk of Bleeding

Question 15

What drugs interact with Amiodarone

Answer 15

-Sodium Bicarbonate, Heparin: Do not mix. Flush line
-Other antiarrhythmics

Question 16

What drugs interact with Adenosine

Answer 16

Caffeine, theophylline: Lowers effects

Question 16

What drugs interact with Diltiazem

Answer 16

Beta Blockers: Synergistic effects

Question 17

What drugs interact with Atropine

Answer 17

Anticholinergics: increased effects

Question 18

What drugs interact with Calcium chloride

Answer 18

Sodium Bicarbonate: Do not mix in same line
Digoxin: Toxicity

Question 19

What drugs interact with Calcium Gluconate

Answer 19

Sodium Bicarbonate: Do not mix in same line
Digoxin: Toxicity

Question 20

What drugs interact with Metoprolol

Answer 20

-Diltiazem, Digoxin: Bradycardia
-Epinephrine: Excessive adrenergic stimulation

Question 21

What drugs interact with Norepinephrine

Answer 21

Beta blockers, TCAs: Hypertension

Question 22

What drugs interact with Heparin

Answer 22

Sodium Bicarbonate, Amiodarone: Incompatible
Anticoagulants: Hemorrhage

Question 23

What drugs interact with Oxytocin

Answer 23

Vasopressors: Hypertension

Question 24

What drugs interact with Tranexamic Acid

Answer 24

Contraceptives: Thrombosis

Question 25

What drugs interact with Dopamine

Answer 25

Sodium Bicarbonate: Incompatible

Question 26

What drugs interact with Furosemide

Answer 26

-Metoprolol: Hypotension and Bradycardia

Question 27

What drugs interact with Magnesium Sulfate

Answer 27

Calcium: Antidote

Question 28

What drugs interact with Albuterol

Answer 28

-Diuretics: If non potassium sparing, may result in hypokalemia -Beta Blockers: Neutralize the effects -Tricyclic antidepressants and MAOIs: Increase effects

Question 29

What drugs interact with Diphenhydramine

Answer 29

-Antihistamines, Alcohol, Opiates, sedative hypnotics: CNS depression -MAOs, Tricyclic antidepressants: Increased anticholinergic effect

Question 30

What drugs interact with Succinylcholine

Answer 30

-Diltiazem, Dexamethasone, methylprednisolone: Prolongs effects -Furosemide: May enhance or dilute effects

Question 31

What drugs interact with Rocuronium

Answer 31

Local anesthetics, beta-adrenergic blockers, potassium depleting diuretics, succinylcholine: Prolongs effects and intensity

Question 32

What drugs interact with Vecuronium

Answer 32

-Etomidate, Ativan, diltiazem, Metoprolol, Nimbex, Reglan: Increases effects -Furosemide: Decreases effects -Methylprednisolone: May cause muscle disorders -Midazolam: May alter effects Anticholinesterases: Reverses effects

Question 33

What drugs interact with Glucagon

Answer 33

-Beta Blockers: Antidote -Epinephrine: Increases duration Phenytoin: Inhibits

Question 34

What drugs interact with Dextrose

Answer 34

Insulin, hypoglycemic agents: Increases dosage needs

Question 35

What drugs interact with Promethazine

Answer 35

-CNS depressants: Increases effects -Antipsychotics: Neuroleptic malignant syndrome -MAO inhibitors and drugs with anticholinergic effects: increases anticholinergic effects

Question 36

What drugs interact with Odansetron

Answer 36

-Apomorphine: Hypotension -Serotonin affecting drugs: Serotonin syndrome

Question 37

What drugs interact with Prochlorperazine

Answer 37

-Anticholinergic drugs: Increases effects -CNS depressants: Increased CNS depression -Nitrates, Antihypertensives: Hypotension

Question 38

What drugs interact with Pralidoxime Chloride

Answer 38

Organophosphate antidote

Question 39

What drugs interact with Activated charcoal

Answer 39

Most drugs

Question 40

What drugs interact with Naloxone HCL

Answer 40

Fentanyl: Antidote

Question 41

What drugs interact with Sodium Bicarbonate

Answer 41

By rule of thumb, just don't mix drugs in a line with sodium. Use a separate one or flush the singular well

Question 42

What drugs interact with Hydroxocobalamin

Answer 42

Use a separate IV, do not mix with other drugs

Question 43

What drugs interact with Acetaminophen

Answer 43

Other acetaminophen containing drugs: Toxicity