Meds for test 1 Flashcards Preview

Nursing Semester 2 (Med surg & Peds) > Meds for test 1 > Flashcards

Flashcards in Meds for test 1 Deck (23)
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1

Common drug therapy for RA:

NSAIDS (short-term use)

DMARDS

Corticosteroids

BRM's

Other immunosuppressive agents

2

Common drug therapy for OA:

NSAIDS (short-term use)

Acetaminophen

other analgesics

3

celecoxib (Celebrex) (Cox 2 inhibitor) is usually first choice unless patient has

Hypertension

kidney disease

Cardiovascular disease

4

Biological response modifier used for RA:

Etanercept (Enbrel - subQ)

Infliximab (Remicade- single IV infusion over several hrs)

Adalimumab (Humira- subQ)

Anakinra (Kineret- subQ)

Abatacept (Orencia- IV)

Rituximab (Rituxan- IV)

Golimumab (Simponi- subQ)

Tocilizumab (Actemra- IV)

5

First-line disease modifying antirheumatic drugs (3)

Methotrexate (Rheumatrex)

Leflunomide (Arava)

Hydroxychloroquine (Plaquenil) -antimalarial, watch for retinal damage

6

Prednisone (deltasone) is a

glucocorticosteroid, fast acting anti-inflammatory and immunosuppressive)

7

Bisphosphonates (abr)

common drug used for osteoporosis

alendronate (Fosamax)

Ibandronate (Boniva)

risedronate (Actonel, Atelvia)

commonly used for prevention and treatment of osteoporosis

8

Drug therapy for osteoporosis

Calcium supplements

Bisphosphonates

Estrogen agonist/antagonist (Raloxifene- Evista)

9

Drug therapy for Paget's disease

NSAID (ibuprofen)

Oral BP's

Calcitonin

10

Normal ESR labs:

male: up to 15 mm/hr

Female: up to 20 mm/hr

11

Normal HsCRP labs:

< 1.0 mg/dl or <10.0 mg/L

12

Normal serum complement C3 & C4 labs

Total: 30-75 units/mL

C3: 75-175 mg/dL;

C4: 22-45 mg/dL

13

Normal SPEP labs:

6.4-8.3 g/dL

14

Drugs that can cause Osteoporosis:

Corticosteroids

Anti-epileptic drugs (phenytoin)

Barbiturates (phenobarbital)

Ethanol (alcohol)

Drugs that induce hypogonadism

High levels of thyroid hormone

Cytotoxic agents

Loop diuretics

Immunosuppressants

15

Osteoporosis clinical manifestations:

dowager's hump or kyphosis of dorsal spine

decreased height

back pain

fractures

no definitive lab tests

16

Osteomalacia clinical manifestations:

early stage- non specific

muscle weakness, bone pain

muscle cramping- hypocalcemia

17

Musculoskeletal manifestations of Paget's disease

bone and joint pain that is aching, poorly described, and aggravated by walking

low back pain and sciatic nerve pain

bowing of long bones

loss of normal spinal curvature

enlarged, thick skull

pathologic fractures

18

Skin manifestations of Paget's disease:

flushed, warm skin

19

Other manifestations of Paget's disease:

apathy, lethargy, fatigue

hyperparathyroidism

gout

urinary or renal stones

heart failure from fluid overload

20

Acute osteomyelitis key features

fever

swelling around area

erythema of affected area

tenderness of area

bone pain that is constant, localized and pulsating, intensifies with movement

21

Chronic osteomyelitis features

foot ulcers (MOST COMMON)

Sinus tract formation

localized pain

drainage from affected area

22

Osteomyelitis diagnostics

CBC

ESR

Blood culture/wound culture

x-rays/CT scan

MRI

Biopsy

23

Osteomyelitis interventions

Non-surgical
- IV antibiotics (Vancomycin)
-PICC line
- Wound care
- Hyperbaric Oxygen therapy

surgical:

sequestrectomy (may be performed to deride the necrotic bone)
amputation