MEDSURG 2 EXAM #2 Flashcards

Week 3 & 4

1
Q
  1. Define dementia and delirium.
A

Dementia: *

___________________
Delirium:* acutely disturbed state of mind
— S/Sx: restlessness, illusions, and incoherence, hyper/hypoactive activities

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2
Q

Dementia differences
Using mnemonic “OCDCAMPS”

A

Onset — insidious (over months to years)
Course — progressively gets worse
Duration — irreversible (months to years)
Consciousness — often normal
Attention — often normal (associated mostly to memory loss)
Memory — immediate recall often normal
Psychomotor changes — not usually present
Sleep-wake cycle — often normal

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3
Q

Delirium differences
Using mnemonic “OCDCAMPS”

A

Onset — rapid (hrs to days)
Course — fluctuating (“sundowning” towards the evening)
Duration — reversible (days to weeks; can cause liver failure)
Consciousness — altered due to something (infection, imbalances, etc)
Attention — significant inattention/lack of concentration)
Memory — immediate recall = impaired
Psychomotor changes — HYPER/HYPOactive
Sleep-wake cycle — often reverse of cycle

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4
Q

Depression differences using mnemonic “OCDCAMPS”

A

Onset — often coincides w/ life changes; often abrupt
Course — variable, rapid to slow, but may be uneven
Duration — several months to years, especially if not treated
Consciousness — feels sense of hopelessness (may not want to live)
Attention — may be indecisive
Memory — intact, but w/ apathy & fatigue
Psychomotor — often withdrawn and hypoactive
Sleep-wake cycle — disturbed, often w/ early AM awakening; can sleep all the time, or not at all

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5
Q

What is delirium + example?

A

Acutely disturbed state of mind, a cognitive impairment due to something
— e.g. fever, intoxication, d/o’s, UTI/infections

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6
Q

What is an illusion + example?

A

Perceiving something differently than what actually exists
— e.g. fearing a shadow is an attacker

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7
Q

Reasons for short-term illness in older adults with delirium?

A

— Lung/heart disease
— Infection
— Poor nutrition
— Drug interaction

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8
Q

Patients who experience delirium are at an increased risk for?

A

— Longer hospitalizations
— Further functional decline
— Institutionalization

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9
Q

The 3 most common cognitive problems in adults are?

A
  1. Delirium (acute confusion)
  2. Dementia
  3. Depression

NOTE: problems often occur together

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10
Q

What is a delusion + example?

A

Believing things that are contradicted by what is generally accepted as relation or rational argument
— e.g. fearing that people are trying to harm you

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11
Q
  1. Classify the different etiologies of dementia.
A

— Can occur following a relatively minor insult in a vulnerable patient
— e.g. Patient w/ underlying health problems (like HF, sensory limitations) may develop delirium in response to a minor change (e.g. use of a sleeping medication)
Nonvulnerable patients may take a combination of factors to precipitate delirium
— e.g. Anesthesia, major surgery, infection

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12
Q
  1. Explain the pathophysiology for different types of dementia.
A
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13
Q

Precipitating Factors for delirium

A

— Demographic characteristics
— Cognitive status
— Environmental
— Functional status
— Sensory
— Decreased oral intake
— Drugs
— Surgery
— Coexisting medical conditions

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14
Q

Mnemonic for causes of delirium

A

D — dementia, dehydration
E — electrolyte imbalance, emotional stress
L — lung, liver, heart, kidney, brain
I — infxn, ICU
R — Rx drugs
I — injury, immobility
U — untreated pain, unfamiliar environment
M — metabolic d/o’s

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15
Q
  1. Discuss the clinical manifestations of mild cognitive impairment.
A

— Manifestations are sometimes confused with dementia and depression
— Usually develops over a 2-3 day period (or w/in hrs)
S/Sx: hypoactive, lethargic, hyperactive, agitated, hallucinating
— acute delirium lasts 1-7 days

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16
Q

Early manifestations of delirium

A

Inability to concentrate
Irritability
Insomnia
Loss of appetite
Restlessness
Confusion

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17
Q

Later manifestations of delirium

A

Agitation
Misperception
Misinterpretation
Hallucinations

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18
Q

Vascular dementia cause

A

also known as multiinfarct dementia
— Loss of cognitive function due to ischemic or hemorrhagic brain lesions caused by CV disease.

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19
Q

Creutzfeldt-Jakob Disease (CJD)

A

A degenerative brain disorder that leads to dementia and, ultimately, death

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20
Q

S/Sx of Creutzfeldt-Jakob Disease (CJD)

A

Can resemble those of other dementia-like brain disorders, such as Alzheimer’s. But Creutzfeldt-Jakob disease usually progresses much more rapidly.

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21
Q
  1. Describe the clinical manifestations, diagnostic studies, and nursing and interprofessional care for a patient with dementia.
A

Dx — focused on determining the cause through medical, neurological, psychological hx, and mental status testing
— only performed to RULE OUT other conditions
— MRI + CT can ID cognitive loss + vascular brain lesions

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22
Q

Dementia with Lewy bodies disease (LBD)

A

abnormal deposits of protein in the brainstem and cortex with manifestations similar to Alzheimer’s (cognitive impairment and hallucinations) and Parkinson’s (bradykinesia, rigidity, and postural instability but not always a tremor).

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23
Q

What is Alzheimer’s Disease (AD)?

A

Chronic, progressive, degenerative disease of the brain. It is the most common form of dementia, accounting for 60% to 80% of all cases of dementia. Exact cause is unknown. Likely a combination of genetic and environmental factors.

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24
Q

Causes of dementia

A
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25
Q

Types of dementias

A

— Neurodegenerative disorders
— Vascular diseases
Immunologic diseases or infections
—Medications
— Systemic diseases
— Trauma
— Tumors
— Ventricular disorders

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26
Q

Causes of dementia: neurodegenerative disorders

A
  • AD
  • Amyotrophic lateral sclerosis (ALS)
  • Dementia with Lewy bodies (DLB)
  • Down syndrome
  • Frontotemporal lobar degeneration (FTLD)
  • Huntington’s disease
  • Parkinson’s disease
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27
Q

Causes of dementia: vascular disease

A
  • Chronic subdural hematoma∗
  • Subarachnoid hemorrhage∗
  • Vascular (multiinfarct) dementia
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28
Q

Causes of dementia: immunologic disease or infections

A
  • Multiple sclerosis
  • Systemic exertion intolerance disease
  • Infections (e.g., Creutzfeldt-Jakob disease)
  • Acquired immunodeficiency syndrome (AIDS)
  • Meningitis∗
  • Encephalitis∗
  • Neurosyphilis∗
  • Systemic lupus erythematosus∗
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29
Q

Causes of dementia: medications

A
  • Anticholinergics
  • Antiparkinsonian drugs
  • Cardiac drugs: digoxin, methyldopa
  • Cocaine
  • Heroin
  • Hypnotics
  • Opioids
  • phenytoin (Dilantin)
  • Tranquilizers
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30
Q

Causes of dementia: metabolic or nutritional diseases

A
  • Alcohol use disorder
  • Cobalamin (vitamin B12) deficiency∗
  • Folate deficiency∗
  • Hyperthyroidism∗
  • Hypothyroidism∗
  • Thiamine (vitamin B1) deficiency∗
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31
Q

Causes of dementia: systemic diseases

A
  • Dialysis dementia∗
  • Hepatic encephalopathy∗
  • Uremic encephalopathy∗
  • Wilson’s disease
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32
Q

Causes of dementia: trauma

A
  • Head injury (potentially reversible)
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33
Q

Causes of dementia: tumors

A
  • Brain tumors (primary)∗
  • Metastatic tumors (potentially reversible)
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34
Q

Causes of dementia: ventricular disorders

A
  • Hydrocephalus (potentially reversible)
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35
Q

Delirium Diagnostic Studies

A

Medical history
Psychologic history
Physical examination
Careful attention to medications
Cognitive measures
Confusion Assessment: Method (CAM)

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36
Q

Dx Studies in Delirium

A

To explore the cause:
— Serum electrolytes
— Blood urea nitrogen level
— Creatinine level
— Complete blood count (CBC)
— Drug and alcohol levels
— Electrocardiogram (ECG)
— Urine analysis
— Liver & Thyroid function tests
— O2 saturation levels
— Lumbar puncture

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37
Q

What is the role of the RN for a patient with delirium?

A

— Prevention
— Early recognition
— Treatment
— Focus on eliminating precipitating factors
— Protect patient from harm
— Encourage family members to stay at bedside
— If delirium is 2ndary to infxn, ABX therapy is next

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38
Q
  1. Discuss the clinical manifestations, diagnostic studies, and nursing and interprofessional care for a patient with Alzheimer disease.
A
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39
Q
  1. Explain the etiology, pathophysiology, clinical manifestations, diagnostic studies, and nursing and interprofessional care for a patient with delirium.
A
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40
Q

RN Mgmt for Delirium

A

Reorientation and behavioral interventions—used in all patients with delirium
Create a safe and quiet environment.
Provide reassurance.
Pay attention to environmental stimuli.
Clocks, calendars, noise, and light levels
Patient experiencing delirium is also at risk for
Immobility
Skin breakdown.
Nurse should also focus on supporting the family and caregivers.

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41
Q

Drug therapy for Delirium

A

— Dexmedetomidine (Precedex) for sedation
— Neuroleptics (antipsychotics, major tranquilizers)
— Haloperidol (Haldol)
— Risperidone (Risperdal)
— Olanzapine (Zyprexa)
— Quetiapine (Seroquel)
— Short-acting benzodiazepines (e.g. Lorazepam (Ativan))

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42
Q
  1. Outline the classification of spinal cord injuries and associated clinical manifestations.
A
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43
Q

Stages of grief

A

— Shock/Denial
— Anger
— Depression
— Bargaining
—Adjustment/Acceptance

44
Q
  1. Describe the clinical manifestations and interprofessional and nursing management of neurogenic and spinal shock.
A
45
Q
  1. Relate the clinical manifestations of spinal cord injury to the level of disruption and rehabilitation potential.
A
46
Q
  1. Describe the nursing management of the patient with a spinal cord injury.
A
47
Q
  1. Explain the types, clinical manifestations, and interprofessional and nursing management of spinal cord tumors.
A
48
Q
  1. Explain the etiology, clinical manifestations, and interprofessional and nursing management of trigeminal neuralgia and Bell’s palsy.
A
49
Q
  1. Describe the etiology, clinical manifestations, and interprofessional and nursing management of Guillain-Barré syndrome and inflammatory demyelinating polyneuropathy.
A
50
Q

What are the clinical manifestations of Alzheimer’s Disease (AD)?

A

51
Q

Genetic factors for Alzheimer’s Disease

A

↑ β-amyloid protein —
> ↑ risk

3 genes important in etiology of AD
Apolipoprotein E (ApoE-2):
ApoE-3:
ApoE-4:
People inherit one allele from each parent

52
Q

Early signs of Alzheimer’s disease

A
  1. Memory loss that affects job skills
  2. Difficulty performing familiar tasks
  3. Problems with language
  4. Disorientation to time and place
  5. Poor or ↓ judgment
  6. Problems with abstract thinking
  7. Misplacing things
  8. Changes in mood or behavior
  9. Changes in personality
  10. Loss of initiative
53
Q

Diagnostic Criteria of Alzheimer’s Disease

A

Changes in the brain:
— May precede symptoms by many years
— May not correlate with behaviors
Spectrum of Alzheimer’s disease:
— Preclinical AD
— Mild cognitive impairment
— Dementia (terminal stage of disease)

54
Q

S/Sx of Dementia

A

— Depression

55
Q

Etiology + Pathophysiology of dementia

A

Predisposed risks of dementia:
— Obesity
— Smoking
— Cardiac dysrhythmias
— Hypertension
— Hypercholesterolemia
— Coronary artery disease

56
Q

Why would older adults be more prone to drug toxicity?

A

Their kidney’s don’t excrete. They’re not drinking enough water to excrete (dehydrated).

57
Q

Delirium also known as

A

ICU psychosis

58
Q

Decipher the different mechanisms of injury

A
59
Q

Which is the most unstable mechanism of injury? Why?

A

Flexion-rotation
— Because ligaments that stabilize the spine are torn
— Injury most often contributes to severe neurological deficits

60
Q

Injuries from C1 to T1 can cause __________ resulting in ___________.

A

Paralysis in ALL 4 extremities resulting in tetraplegia/quadriplegia

61
Q

Definition of paraplegia + SCI occurrence location

A

Paralysis and loss of sensation in the legs
Location: below T2

62
Q

Differences in C4, C6, T6, & L1 spinal cord injuries

A

C4 (cervical) — tetraplegia (below the neck)
C6 (thoracic) — partial paralysis of hands and arms and lower body
T6 (lumbar) — paraplegia below chest
L1 (sacral) — paraplegia below the waist

NOTE: “C3, 4, & 5, keeps the diaphragm alive!”

63
Q

After suspecting a TIA or stroke, which diagnostic tests might the patient need for further assessment?

A

— Non-contrast head CT/MRI
— CT angiography (CTA)
— Angiography
— Intraarterial digital subtraction angiography (DSA)

64
Q

ASIA Impairment Scale is used for what

A

classifying the severity of impairment resulting from spinal cord injury
— combines assessments of motor and sensory function to determine neurological level and completeness of injury

64
Q

ASIA Impairment Scale is used for what

A

classifying the severity of impairment resulting from spinal cord injury
— combines assessments of motor and sensory function to determine neurological level and completeness of injury

65
Q

What is Trigeminal Neuralgia?

A

trigeminal nerve CN V
— Characterized by sudden, usually unilateral, severe, brief, stabbing, recurrent episodes of pain in the distribution of the trigeminal nerve
— Both motor and sensory branches and usually affects sensory (mainly maxillary and mandibular branches)
— * Most cases result from vascular compression of the trigeminal nerve root by an abnormal loop of the superior cerebellar artery.
— Abnormal loop of the superior cerebella’s artery, which compresses the nerve as it exits the brainstem. This leads to chronic injury, causing flattening and atrophy of the nerve and damage to the myelin sheath
— Underlying pathology (MS, shingles, masses in cerebellum/brainstem)

66
Q

Causes of trigeminal neuralgia (CN V)

A
  • Painful episodes are usually initiated by a triggering mechanism of light touch at a specific point (trigger zone) along the distribution of the nerve branches.
  • The pain intensity and disruption of lifestyle can result in marked physical and psychologic dysfunction.
67
Q

How to relieve trigeminal neuralgia?

A

— Antiepileptic/seizure medications (less effective in TN2)
— Analgesics/Opioids for pain with TN2
— Nerve blocking with local anesthetics
— Surgical therapy is last option (Percutaneous procedures where nerve fibers are damaged to eliminate pain; relief lasts longest with micro vascular decompression w/ 1/2 of patients with recurrent pain in 12-15 years)

68
Q

Meds to relieve trigeminal neuralgia?

A

Carbamazepine (gold std, but HIGH S/Sx)
Phenytoin (Dilantin)
Gabapentin (Neurontin)
Lamotrigine (Lamictal)
Oxcarbazepine (Trileptal)
Topiramate (Topamax)

69
Q

S/Sx of trigeminal neuralgia 1

A

— Abrupt onset of waves of excruciating pain.
— Burning, knifelike, or lightning-like shock in the lips, upper or lower gums, cheek, forehead, or side of the nose
— Facial twitching, grimacing, and frequent blinking and tearing of the eye can occur during the acute attack (giving rise to the term tic douloureux)
— Some patients may have facial sensory loss. — Attacks are usually brief, lasting only seconds to 2 or 3 minutes
— Frequency ranges from 1 to over 50 times a day.

70
Q

S/Sx of trigeminal neuralgia 2

A

— Constant aching, burning, crushing, or stabbing pain
— The pain has a lower intensity and does not subside completely
— The distinct attacks associated with TN 1 do not occur in TN 2.

71
Q

Dx of trigeminal neuralgia

A

— Complete physical and neurological examinations & assessments are performed so other d/o that cause facial pain are ruled out before TN is Dx’d
— MRI
— 3D reconstruction + angiography MRI (sees specific brain anatomy, nerve roots, and vascular use involved)
— Subspecialties for consultation: neurology, neuroradiology, neurosurgery, dentistry, maxillofacial surgery, and pain management.

72
Q

S/Sx of Bell’s Palsy

A
73
Q

Bell’s Palsy

A

CN VIII
— acute, usually temporary, facial paresis (or palsy) resulting from damage or trauma of the facial nerve
— most common facial nerve disorder

74
Q

RF for Bell’s Palsy

A

— High incidence during pregnancy
— Upper respiratory tract conditions (e.g. flu, colds)
— Obesity
— Diabetes Mellitus
— HTN

75
Q

Clinical manifestation for Bell’s Palsy

A

— Acute onset of unilateral lower motor facial weakness
— Pain around/behind ear/neck (50-60%)
— Drooping eyelid and corner of mouth
— Drooling
— Facial twitching
— Dryness of eyes/mouth
— Facial numbness
— Altered taste
— Hearing loss
— Excessive tearing in 1 eye

NOTE: most S/Sx will begin suddenly and reach their peak w/in 48-72 hrs

76
Q

Treatment for Bell’s Palsy

A

— Oral corticosteroids
— Most heat
— Pain mgmt
— Electrical nerve stimulation
— Prescribed exercises

NOTE: normally will begin to feel better w/in 2 weeks after onset. Recovery of some or all facial function w/in 6months.

77
Q

Guillain-Barré Syndrome

A

— An acute, rapidly progressing, and potentially fatal form of polyneuropathy
— Affects the peripheral nervous system
— Results in loss of myelin and edema and inflammation of the affected nerves. This causes a loss of neurotransmission to the periphery.

78
Q

RF for Guillain-Barré Syndrome

A
79
Q

Guillain-Barré Syndrome clinical manifestations

A
80
Q

Treatment for Guillain-Barré Syndrome

A
  • The most serious complication is respiratory failure. It occurs due to paralysis progressing to the nerves that innervate the thoracic area. Constant monitoring of the respiratory system provides information about the need for immediate intervention.* Management is aimed at supportive care, particularly ventilator and hemodynamic support, during the acute phase. The objective of nursing care is to support the body systems until the patient recovers.
81
Q

S/Sx of Botulism

A
82
Q

Treatments for Tetanus symptoms

A
83
Q

Causes of SCI

A

Usually from trauma
38% motor vehicle collisions
30% falls
14% violence
9% sports injuries
9% other miscellaneous cases

84
Q

What are of penetrating trauma that can result in tearing and transaction of spinal cord?

A

Gunshot wound
Stab wounds

85
Q

Causes of initial injury of spinal cord

A

— Due to cord compression by bone displacement
— Interruption of blood supply
— Traction from pulling on cord
— Penetrating trauma —> tearing and transaction (rarely torn or transected by direct trauma due to being wrapped in tough layers of dura)

86
Q

Difference of 1ary vs 2ndary injury

A

Primary (1ary) — initial mechanical disruption of axons as a result of stretch or laceration
Secondary (2ndary) — ongoing, progressive damage that occurs after initial injury

86
Q

ASIA Impairment Scale is used for what

A

classifying the severity of impairment resulting from spinal cord injury
— combines assessments of motor and sensory function to determine neurological level and completeness of injury

87
Q

Pathology of Initial Injury

A

— By ≤24 hours, permanent damage may occur because of edema.
— Extent of damage from both primary injury and secondary injury (edema = harmful b/c of lack of space for tissue expansion causing compression of spinal cord occurs)
— Ischemic damage when edema extends above AND below the injury
— Prognosis cannot be determined for at least 72 hours.

87
Q

ASIA Impairment Scale is used for what

A

classifying the severity of impairment resulting from spinal cord injury
— combines assessments of motor and sensory function to determine neurological level and completeness of injury

88
Q

Spinal shock is characterized by?

A

↓ Reflexes
Loss of sensation
Flaccid paralysis below level of injury
Lasts days to months

88
Q

ASIA Impairment Scale is used for what

A

classifying the severity of impairment resulting from spinal cord injury
— combines assessments of motor and sensory function to determine neurological level and completeness of injury

89
Q

Neurogenic shock

A

Characterized by
Hypotension
Bradycardia

Loss of SNS innervation
Peripheral vasodilation
Venous pooling
↓Cardiac output
T6 or higher injury

89
Q

ASIA Impairment Scale is used for what

A

classifying the severity of impairment resulting from spinal cord injury
— combines assessments of motor and sensory function to determine neurological level and completeness of injury

90
Q

Levels of injury

A

Skeletal vs. neurologic level
Level of injury may be
Cervical
Thoracic
Lumbar
Tetraplegia (quadraplegia)
Paraplegia

90
Q

ASIA Impairment Scale is used for what

A

classifying the severity of impairment resulting from spinal cord injury
— combines assessments of motor and sensory function to determine neurological level and completeness of injury

91
Q

Skeletal vs. Neurological level of injury

A

Skeletal
— vertebral level where there is the most damage to vertebral bones and ligaments

Neurological
— lowest segment of the spinal cord with normal sensory and motor function on both sides of the body
— may be cervical, thoracic, lumbar, or sacral

91
Q

ASIA Impairment Scale is used for what

A

classifying the severity of impairment resulting from spinal cord injury
— combines assessments of motor and sensory function to determine neurological level and completeness of injury

92
Q

Complete vs Incomplete injury

A

Complete
— Total loss of sensory and motor function below level of injury

Incomplete (partial)
— Mixed loss of voluntary motor activity and sensation (some tracts intact)

93
Q

Injuries ABOVE level of C4

A

Total loss of respiratory muscle function
— Patient must be on mechanical ventilation

94
Q

Injuries BELOW level of C4

A

Diaphragmatic breathing
— respiratory insufficiency

95
Q

Clinical manifestations of respiratory system

A

Cervical and thoracic injuries
Paralysis of abdominal and intercostal muscles → ineffective cough → atelectasis or pneumonia
↑Risk for infection
Risk for neurogenic pulmonary edema

96
Q

CV system manifestations after SCI

A

Injury above level T6 ↓influence of sympathetic nervous system
Bradycardia
Peripheral vasodilation → hypotension
Relative hypovolemia because of ↑ in venous capacitance
Cardiac monitoring necessary
Atropine to ↑ heart rate
Peripheral vasodilation
↓ Venous return of blood to heart
↓ Cardiac output
IV fluids or vasopressor drugs to ↑ BP

97
Q

Clinical manifestation of urinary system after SCI

A

Acute phase
Urinary retention
Bladder atonic and overdistended
Indwelling catheter
Postacute phase
Bladder may become hyperirritable.
Loss of inhibition from brain
Reflex emptying

98
Q

Integumentary System after SCI

A

Potential for skin breakdown
Poikilothermism (cold-blooded)
Interruption of SNS
↓Ability to sweat or shiver
More common with high cervical injury