Memory Flashcards

(37 cards)

1
Q

Define learning

A

Acquisition of information

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2
Q

Define memory

A

Storage of learned information

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3
Q

Define recall

A

Reacquisition of stored information

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4
Q

Define the engram

A

Physical embodiment of a memory

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5
Q

What is procedural memory

A

Skills and associations
- Largely unavailable to conscious minds
- Changes in the brain when these skills are learned

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6
Q

What is declarative memory?

A

Facts or evens
- Available to conscious mind
- Can be taught
Encoded in symbols and language

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7
Q

What is explicit memory?

A

Memory can be consciously recalled

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8
Q

What is implicit memory?

A

Memory that cannot be consciously recalled

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9
Q

What are the different types of implicit memory?

A

Procedural memory
Classical conditioning
Priming (one stimulus influences the response to subsequent stimuli)

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10
Q

Duration of immediate memory

A

Few seconds

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11
Q

Duration of short term memory

A

Seconds or minutes

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12
Q

Duration of long term memory

A

Days, months or years

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13
Q

What is working memory?

A

Memories are immediately memorised in a loop but are not stored in long term

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14
Q

Describe patient HM

A

Temporal lobotomy of epileptic part of brain
- New memories weren’t able to be formed
(Anterograde amnesia)

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15
Q

What memory is processed in the frontal lobe?

A

The working memory

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16
Q

What memory is processed in the hippocampus?

A

Converting short to long term
- Declarative
- Spatial memory formation

17
Q

What occurs in the amygdala?

A

Multiple, processed sensory inputs
Implicit, emotional and learnt fear

18
Q

What memory is processed in the cerebellum?

A

Procedural
Sensorimotor

19
Q

What do hippocampus lesions cause?

A

Formation of new memories is lost

20
Q

Describe the structure of the hippocampus

A

Three layered cortex

21
Q

Where are the hippocampus inputs?

A

Entorhinal cortex

22
Q

How does a connection between 2 neurons become stronger?

A

They must be active (spiking) at the same time

23
Q

What is the Hebbian synapse concept?

A

Activity is modifiable in neurons
Synapses are plastic

24
Q

Define facilitation

A

An increase in synapse strength

25
Describe depression in a synapse
A weakened synapse with less postsynaptic effect
26
What is short term facilitation?
Vesicle depletion - The synapse is weaker due to less vesicles to transport neurotransmitters
27
What is long term potentiation?
Persistent strengthening of synapses leading to long lasting increases in synaptic transmission between neurons
28
Where does LTP occur?
In the Hippocampus between CA3 neuron and CA1 neuron (pre and postsynaptic neurons)
29
How does LTP affect the EPSP?
Increases EPSP amplitude
30
How does LTD affect the EPSP?
Decreases EPSP amplitude
31
Define sensitisation
Increased response to the same stimulus leads to modification
32
What is habituation?
Memory formation due to repeated behaviours
33
What do changes in synaptic strength require?
Receptor activation of glutamate and serotonin
34
What are LTP, LTD and APLYSIA mediated by?
Second messenger (Ca2+ and cAMP)
35
How does LTP occur?
Pre synapse is filled with glutamate release neurotransmitter into cleft -> Recognised by receptors
36
Action of AMPA receptor
Depolarises the membrane
37
Action of NDMA receptor
Release Ca2+ into post synaptic neuron, activates protein kinase -> Phosphorylates proteins and increased the activity of AMPA