Mendelian Inheritance Flashcards
What are the features of autosomal dominant inheritance?
Each generation is affected
Both sexes affected in equal proportion
Equal transmission
Transmitted through infected individuals
What are the features of autosomal recessive inheritance?
Affected individuals in a single generation
Generations are skipped
Both sexes are affected in equal proportion
Give an example of a dominant autosomal disease
Achondroplasia
(affects fibroblast growth factor receptor protein)
Why can a father never pass on an X linked condition to his son?
Male only pass on Y chromosomes to sons
X chromosomes are passed on only form mother
Who can transmit an X related condition?
Mother can transmit to son or daughter
Father can only transit to daughter
Can a female ever get haemophilia?
(improper blot clotting)
Yes, if parents are affected male and carrying mother
