Metabolism Flashcards

1
Q

What does lactate dehydrogenase do

A

convert pyruvate into lactate

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2
Q

If oxygen is available, what can lactate be converted to?

A

pyruvate

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3
Q

Where does Glycoolysis take place?

A

cytosol

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4
Q

Where do the krebs and electron transport chain occur

A

mitochondria

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5
Q

how many ATP does Glycolysis produce (net)

A

2

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6
Q

How many molecules of ATP are produced when a glucose molecule goes through a full cycle of oxidative reactions?

A

36

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7
Q

How are the Krebs cycle and the electron transport Chain connected in the metabolic pathway?

A

Krebs cycle binds NAD+ and FAD+ with hydrogen ions to ETC

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8
Q

What is Pyruvate made into in the first step of the Krebs cycle

A

Acetyl CoA

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9
Q

Oxaloacetic acid is produced by the breakdown of ______ in ______

A

pyruvate, glycolysis

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10
Q

oxaloacetic acid is the pickup molecule for ______ in the Krebs cycle to make citric acid (initial reactant)

A

Acetyl CoA

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11
Q

How is the majorit of lactate produced in skeletal muscle metabolic reactions?

A

During anaerobic exercise (oxygen isn’t always available) when there are plenty of hydrogen ions available

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12
Q

H is oxidized at a relatively steady rate in which type of glycolysis

A

aerobic

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13
Q

Where will Lactate go if it is not immediately converted back to pyruvate?

A

Liver (cori cycle). there it is converted to pyruvate or glycogen

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14
Q

Why are hormones important to fat breakdown

A

Hormones help produce cyclic AMP which activates hormone-sensitive lipase that starts the breakdown of fat

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15
Q

ATP yield per molecule of neutral fat

A

460

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16
Q

Hormone sensitive lipase breaks down triglyceride into

A

glycerol + 3 Fatty acids

17
Q

1 molecule of glycerol will yield ____ ATP through Glycolysis and Citric acid cycle

A

19

18
Q

3 molecules of 18-carbon fatty acid will yield ____ molecules of ATP through beta oxidation and krebs cycle (citric acid cycle)

A

441

19
Q

When is fat breakdown inhibited (3 things)

A

excess ketones, excess circulating lactate, lack of insulin to mobilize blood glucose

20
Q

What must proteins (amino acids) be converted into before they can go into glycolysis or the krebs cycle?

A

keto acid

21
Q

Besides Keto acids, what else does amino acids break down into?

A

NH3 -> urea -> excreted in urine

22
Q

Study the Glycolysis cycle

A

DO IT

23
Q

Immediate sources of fuel in metabolism

A

ATP, CP, ADP’s

24
Q

Short term fuel in metabolism

A

glycolysis- anaerobic

25
Q

What enzyme uses the potential energy of ATP

A

ATPase - breaks it down into ADP and P