Methoxyflurane

Question 1

What are the indications for Methoxyflurane?

Answer 1

Moderate to severe pain, when there will be a significant delay in an opiate being administered.

Question 2

What are the contraindications for methoxyflurane?

Answer 2

• Known severe allergy.
• Personal or family history of malignant hyperthermia.
• Known renal impairment.
• Methoxyflurane administered within the last week.

Question 3

What are the precautions for methoxyflurane?

Answer 3

• Age greater than or equal to 75 years, particularly if frail.
• Pre-eclampsia.
• Administration within a confined space.
• Acute exacerbation of chronic pain.

Question 4

What are the dosages for methoxyflurane?

Answer 4

• Maximum of 6 ml (two doses) for a patient aged greater than or equal to 12 years.
• Maximum of 3 ml (one dose) for a child aged less than 12 years.

Question 5

What are the usual preparations for methoxyflurane?

Answer 5

3 ml bottle accompanying a plastic inhaler.

Question 6

What is the MOA for methoxyflurane?

Answer 6

Methoxyflurane is an inhalational analgesic.
The mechanism of action is not clear.