Micro 4- Pathogenic properties and control mechanisms Flashcards Preview

ABS > Micro 4- Pathogenic properties and control mechanisms > Flashcards

Flashcards in Micro 4- Pathogenic properties and control mechanisms Deck (10):

what are cytopathic effects? (CPE)

are visible effects of viral infection on a cell


list of CPE- pathogenic properties of viruses

-stopping cell synthesis
-causing cell lysosomes to release enzymes
-changing host cell function or inducing chromosomal changes
-inducing antigenic changes on the cell surface
-loss of contact inhibition in the cell, leading to cancer
-producing interferons to protect uninfected cells
-creating inclusion bodies in the cell cytoplasm
-fusing cells to create syncytium


3 host defense mechanisms

-cell mediated immunity


what are interferons?

cytokines produced by lymphocytes and macrophages, have antiviral activity


effect of IFN-a and IFN- b

produced in response to viral infections, cause neighboring cells to produce antiviral proteins (AVPs) that interfere with viral replication


IFN- y

induces neutrophils and macrophages to kill bacteria


antigen-antibody complex forms when

antibodies bind to antigens
-block attachment of viruses to host cells
-cause viruses to agglutinate


cell-mediated immunity

-cytotoxic T lymphocytes (CTL) recognizes and kills self-cells altered by infection
-destroys virus-infected and cancer cells



-provokes a primary immune response
-leads to the formation of antibodies and long-term memory cells
-stimulated memory cells produce a rapid, intense secondary response


antimicrobial biocides

-lipid-soluble, most likely effective against envelope virus
-fewer biocides are active against non-enveloped viruses