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BLOCK 1 > MICRO: ANAEROBES > Flashcards

MICRO: ANAEROBES Flashcards

1
Q

Bacteria which grows equally well in absence or presence of oxygen

A

Facultative anaerobe

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2
Q

Grow in low oxygen and better when CO2 is increased

A

Microaerophile

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3
Q

Aerotolerant anaerobe

A

Able to grow 2-8% oxygen

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4
Q

Will grow if oxygen is greater that 0.5%

A

obligate anaerobe

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5
Q

The ubiquitous species of bacteria which are the commensals of skin, respiratory, intestinal, and urogenital tract

A

characteristics of anaerobe

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6
Q

Source of infecting microbe / source of the infective anaerobes?

A

Host’s endogenous flora

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7
Q

This bacterial species is weak, but is involved in polymicrobial infection with aerobes

A

Anaerobes

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8
Q

The bacterial species causing abscess formation, tissue necrosis, and often gas formation.

Some produce most potent paralytic toxins.

A
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9
Q

Found in soil, water, food, animals.

A

Anaerobes

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10
Q

Infection with this anaerobes is both_________and _________

A

endogenous and exogenous

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11
Q

Exogenous infection of humans by anaerobes is from…

A

Spore-forming organisms in soil, water, seawage

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12
Q

Endogenous infection of human by anaerobe is from…

A

endogenous flora

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13
Q

Anaerobes which are a normal floras of the skin

A

-Propionibacterium
- Peptostreptococcus

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14
Q

Anaerobes which are a normal flora of the upper respiratory tract?

A

-Propionobacterium

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15
Q

Anaerobes which are a normal flora of the mouth?

A

-Fusobacterium,
- Actinomyces

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16
Q

Anaerobes which are a normal flora of the small intestine?…

A

-clostridium
-bacteroides
-fusobacterium

17
Q

Anaerobes which are a normal flora of the vagina…?

A

Lactobacillus

18
Q

How infection via exogenous route occurs?

A

The anaerobic bacteria gains access via ingestion of contaminated food/water, trauma, or disruption of body surfaces

19
Q

How infection via exogenous route occurs?

A

The anaerobic bacteria gains entry via disruption/trauma of mucous membranes____which allows entry of organism into normally sterile sites

20
Q

Clinical features suggestive of anaerobic infections?…

A
  • Foul smelling discharge
    -Infection associated with malignancy
    -Blood containing exudates
    -Abscess, black necrotic tissue, gangrene

(check more on notes)

21
Q

Factors predisposing to anaerobic infection?

A
  • co-infection with aerobic infection
  • immunosuppression

*check notes

22
Q

A spore forming bacilli which causes tetanus?…

A

Clostridium tetani

23
Q

How clostridium cause tetanus?

A

Produce a neurotoxin, (tetanospasm) which targets
pre synaptic nerve terminal, blocks release of inhibitory neurotransmitter (GABA) into synapses.

-prolonged muscle spasms, rigidity, respiratory arrest and death result if toxin dose is high

24
Q

A spore forming bacilli which causes soft tissue, and enteric (food poisoning) infections?…

A

Clostridium perfringens

*check notes for examples of soft tissue and enteric infections

25
Q

With this highly resistant spore forming bacteria we see food borne infections, wound infections, and neonatal infections.

A

Clostridium botulinum

*It’s the reason we do not give kids honey

26
Q

This an anaerobic bacteria which causes pseudomembranous colitis

  • Cause nosocomial infections as well
A

Clostridium difficile

27
Q

A gram positive spore forming bacilli

A

All clostridium spp

28
Q

A gram positive Non-spore forming bacilli

A

-propionibacterium
-Uebacterium
-Actinomyces

*more on notes

29
Q

A gam positive non-spore forming gram positive cocci

A

peptostreptococcus

30
Q

A gram negative cocci

A

veillonella (Normal oral flora)

-isolated from human bites

31
Q

A gram negative bacilli

A

Bacteroides fragilis (causes vincent’s angina)

*more on notes

32
Q

For accurate diagnoses of anaerobic infection, u must…

A
  • Collect specimen from site containing necrotic tissue
  • Aspirated material or tissue are the preferred specimen types not swabs
33
Q

T/F: After sample collection for anaerobe testing, sample must be incubated anaerobically for 48 hours?…

A

True

Avoid oxygen coz sample will die

34
Q

Appropriate sample types when testing for presence of anaerobes?

A
  • Aspirated material from abscess
  • Tissue
  • Sterile fluid (CSF)
  • Pulmonary secretions
  • GIT (BILE)
  • GUT samples (genitourinary)

BLOCK 1 (18 decks)

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