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ENT Year 2 Medicine > Microbiology > Flashcards

Flashcards in Microbiology Deck (71)
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1

What type of HSV causes oral lesions?

HSV1

2

In regards to HSV what is its main method of infection?

Saliva

3

What is the name given to the primary HSV1 infection?

Primary Gingivostomatitis

4

Who is mainly affected with primary gingivostomatitis?

Young school children generally pre school.

5

What is the clinical presentation of someone with gingivostomatitis?

Systemic upset
Fever
Vesicles - lips buccal cavity and hard palate
Ulcers

6

Generally primary gingivostomatitis requires acyclovir ? T/F?

Generally self resolving , if not then acyclovir is used in severe or unresolved cases.

7

What happens post primary HSV1 infection?

The virus sits within the sensory nerve cells until reactivated, not all reactivations are symptomatic.

8

What is a secondary reactivation of HSV1 commonly called?

A cold sore

9

In regards to cold sores what is the natural history?

A decreasing frequency of reactivations

10

What is used to detect and diagnose HSV1 latency and infection?

Viral PCR swab

11

What is the causative organism in herpangina?

Coxsackie virus
Enterovirus

12

What is the clinal presentation of herpangina?

Vesicles and ulcers on the soft palate

13

What is used to make a diagnosis of herpangina and Hand Foot and Mouth ?

Viral PCR

14

What is the clinical presentation of Hand Foot and Mouth?

Ulcers within the mouth.
Blistering ulcers on the foot and hand
High fever
Family outbreak

15

What is the causative organism in Hand Foot and Mouth?

Coxsackie virus

16

What is the causative organism in syphilis?

Treponema Pallidum

17

What is the main clinical sign of a primary syphilis infection?

Chancre- painless ulcer at the site of the ulcer
- Oral or genital usually

18

Why is it key to diagnose and treat a primary syphilis infection early?

It can progress to secondary and then tertiary syphilis both of which are damaging and ultimately fatal.

19

What are apthous ulcers?

Non viral and self limiting ulcers
Round or ovoid with an inflammatory halo

20

If there is a history of recurrent apthous ulcers what should you be worried about?

A underlying systemic disease

21

List some diseases which are linked to apthous ulcers.

Behcets
IBD
Reiters
Drug reactions
Skin diseases

22

How would behcets present?

Middle East or asian
Recurrent genital or oral ulcers
Uveitis
Visceral organ involvement

23

How would IBD or gluten intolerance present?

Diarrhoea
Weight loss
Recurrent genital or oral ulcers

24

How would reiters present?

Arthritis

25

What skin diseases are linked to apthous ulcers?

Lichen planus
Pemphigus
Pemphigoid

26

What are the two common causes of pain at the back of the throat?

Acute pharyngitis
Tonsilitis

27

What are the common causative organisms for acute pharyngitis or Tonsillitis?

Influenza
Strep infection

28

If the sore throat lasts into the second week what should be suspected?

Glandular fever

29

List some less common causes of a sore throat?

HIV
Gonococcal pharyngitis
Diptheria

30

What physical irritants can lead to a sore throat?

GORD
Cigarette smoke
Alcohol
Hay fever