microbiology ch14 ( neisseriaceae, veillonella, parvobacteria, capnocytophaga Flashcards Preview

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Flashcards in microbiology ch14 ( neisseriaceae, veillonella, parvobacteria, capnocytophaga Deck (25):
1

2 pathogenic genera of Neisseriaceae

Neisseria, Moraxella

2

Neisseria include

Ngonorrhoeae-most frequently diagnosed veneral disease in w. europe and usa. It causes PID, sterility in woman and arthritis and sptecemia
N. meningitidis- causes meningococcal meningitis which is highly contagious and kills up to 80%

3

Neisseriaceae are capnophillic which means

require more CO2 for growth

4

N Gonhorrhoeae

genital tract, oral, nasopharyngeal, rectal carriage, gram neg.

5

describe N gonhorrhoeae's pathogenicity

Pili for adhesion
IgA proteases ( some)
Beta lactamase- beta lactam drugs are ineffective
tracheal cytotoxin- damages ciliated cells of the fallopian tubes causing sterility

6

neisseria meningitidis

nasopharynx, spreads to blood stream and meninges in susceptible people. treated with penicillin or cefotaxime

7

non pathogenic neisseria include...

n. subflava, n. mucosa, n sicca

8

whats the difference between non pathogenic and pathogenic neisseria?

non pathogenic neisseria can develop on agar in absence of CO2

9

Neisseria species in Dental field

Neisseria species are among earliest colonizers of clean tooth surface. They consume oxygen during the early plaque formation and facilitate subsequent growth of facultative and obligate anaerobic late colonizers

10

Moraxella

gram neg., closely related to neisseria species, respiratory tract, cause meningitis, endocarditis, otis media, most produce beta lactamse which can indireclt protect other pathogens

11

veillonella in general

gram negative, is oral samples

12

veillonella parvula

gram neg, in oral cavity and mostly in dental plaque, metabolize lactic acid produced by cariogenic bacteria into weaker acids with reduced ability to solubilize enamel

13

Parvobacteria

Gram neg. , include haemophilus, brucella, bordatella, pasteurella, francisella, gardnerella, eikenella

14

Haemophilus

Requires X and V factors to grow, causes bronchitis, epiglottitis, meningitis, sinusitis, otis media, osteomyelitis, arthritis

15

what is X and V factors?

X- haematin present in blood
V- nicotinamide adenine dinucleotide ( NAD), or NAD-phosphate which is a vitamin produced as a metabolic product of most bacteria

16

Haemophilus influenzae

upper respiratory tract, gram neg., virulent strains have capsules, requires V and X factors, causes meningitis, acute epiglottitis, osteomyelitis, arthritis, Treated by ampicillin,

17

Haemophilus influenzae shows satellitism. What is this?

where it grows around other bacteria that are producing V and X factors

18

virulence factors of haemophilus influenzae

polysacharide capsule, IgA protease which slows and causes incoordination of ciliary action of respiratory tract

19

Bordetella pertussis

upper respiratory tract of diseased folks,( not in healthy people),causes whooping cough, treated by erythromycin, antibiotics have little effect but can help reduce spread

20

what medium is used for bordetella pertussis?

gengou medium, blood charcoal agar supplemented with antibiotics for growth

21

Aggregatibacter actinomycetemcomitans

oral cavity, periodontal disease, subgingival sites, gamma haemolytic, grows best aerobically with 5-10% carbon dioxide, Treated with tetracycline

22

what are the virulence factors of a. actinomycetemcomitans?

endotoxin, leukotoxin, collagenase, cytolethal distending toxin, epitheliotoxin, protease cleaving IgG

23

what does leukotoxin do?

it subverts the host immune response in the gingival crevice

24

Eikenella

found in oral cavity and intestine, capnophilic, gram negative

25

capnocytophaga

this genus was created for fusiform species isolated from periodontal pockets, need capnophilic conditions, found in subgingival regions, some produce igA1 proteases