Microbiology-Hygiene Theory Flashcards Preview

Multisystems II > Microbiology-Hygiene Theory > Flashcards

Flashcards in Microbiology-Hygiene Theory Deck (5)
Loading flashcards...
1
Q

Hygiene hypothesis

A

Increased hygiene has contributed to the increasing rates of autoimmune diseases.

2
Q

In a large family, what child is most likely to have hay fever?

A

The oldest. It is possible that having lots of infections is protective against autoimmunity and youngest children will have less incidence of hay fever.

3
Q

Cytokines produces by T-cells when a person has worm infection

A

IL-4, IL-5, IL-13

4
Q

A 29 year old lived in Africa for 6 years. One of his friends had a worm crawl across the front of his eye and had microfilaria in his blood. He gets a blood test and results are shown below.

A

He has tons of microfilaria in his blood. When people are acutely infected with worms you get eosinophilia and release of IL-4 and IL-5 with allergic symptoms. Chronically, IgG4, IL-10 and TGF-beta that decrease allergic reactivity and T-cell responses.

5
Q

What type of immunity do worms develop

A

Type II with increased IgE and eosinophilia