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Flashcards in Microcirculation Deck (7):
1

Lymphedema

Damage to lymph ducts causes scarring and fluid buildup w/in tissue
Filariasis (worm) is most common cause

2

Hypoxic pulmonary vasoconstriction

Hypoxic pulmonary capillaries constrict and shunt blood to non-hypoxic alveoli
Problem for premies w/ low O2 tension and COPDers b/c it creates pulmonary hypertension and R heart failure

3

What determines diameter of precapillary sphincters?

ANS
Hormones
Local metabolic substances - epi (d/c), histamines (d), serotonin (vascular spasm), prostaglandins (d/c), nitric oxide (d)
Increased temp

4

Types of autoregulation for blood flow

Myogenic - stretch vascular smooth muscle and it contracts
Metabolic - high CO2, lactate, H+, nitric oxide, etc cause dilation; high O2 causes constriction

5

Pitting edema

Impressions left in skin - nonspecific, may indicate heart failure

6

Nitric oxide as vasodilator

Made by endothelial cells, released triggered by bradykinin

7

Organs that autoregulate blood flow

Brain and kidney - as long as systolic pressure is b/w 50-150 mmHg