Micturition Flashcards

(44 cards)

1
Q

Where does sensory feedback from the brain regarding whether or not its socially acceptable to urinate travel along

A

Pelvic nerves

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2
Q

What are the roots of the pelvic nerves

A

S2,3,4

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3
Q

Where does micturation centre send impulses if it is socially acceptable to urinate

A

Through pudendal nerve to sphincter

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4
Q

2 things that the bladder does

A

Emptying and storage

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5
Q

What happens to the bladder during bladder villing

A

Relaxed detrusor
Urethra contracted
Pelvic floor contracted

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6
Q

What happens during the emptying phase to the bladder

A

Detrusor contracts
Urethra relaxes
Pelvic floor relaxes

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7
Q

How many times does the average adult wee per day

A

4

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8
Q

How much urine is passed a day

A

1500ml

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9
Q

What causes normal bladder contraction

A

Ach released from cholinergic nerves

Stimulates muscarinic receptors on the detrusor smooth muscle

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10
Q

What are the receptor abnormalities seen in a ‘weak’ bladder

A

Receptors are not upregulated

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11
Q

What is the problem with a small thickened bladder

A

High pressure during storage phase which can transmit up to kidneys killing them

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12
Q

2 categories of lower urinary tract symptoms

A
  • Storage symptoms

- Voiding symptoms

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13
Q

Some examples of storage symptoms (lower urinary tract)

A

Frequency
Nocturia
Urgency
Urge incontinence

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14
Q

Some examples of voiding/ obstructive symptoms

A

Hesistancy, straining, poor floow, intermittency, incomplete emptying, terminal dribbling, haematuria

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15
Q

What is overactive bladder syndrome

A

Urgency, with or without incontinence, usually with frequency and nocturia

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16
Q

Define nocturia

A

Excessive urination at night

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17
Q

What are the values for mild symptoms on IPSS

A

0-7

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18
Q

What are values for medium and severe symptoms on IPSS

19
Q

Are men or women more affected by urine problem

20
Q

What investigations can be done in patients with urine problems

A
  • Inspect fresh urine sample
  • Dipstick
  • FBC
    Uroflowmetry and post void residual volume
  • Urodynamics
  • XB KUB
  • Ultrasound
  • CT KUB
  • Nuclear imaging
21
Q

What problems with ‘outlet’ can occur

A
Bladder neck problems
Prostate problems
Stricture
Meatus
Foreskin tightening
22
Q

What problems with the pump can occur

A

Bladder- OAB, sensory, failure
Cardiac
Medication

23
Q

What problems with the constituents can occur

A

UTI
Cancer
Inflammation
Stones

24
Q

How does caffeine make your bladder act

A

Releases calcium stores from the golgi apparatus in the bladder wall
Makes bladder contraction more likely

25
How long does the bladder store urine for
3-4 hours
26
Give some examples of medical therapy for urine problems
Alpha blockers (stretchers) 5-alpha reductase inhibitors (shrinkers) PDE5 inhibitors Antimuscarinics
27
What is the gold standard for surgery
TURP | This is when electric loop carves out prostate chips
28
What are the risk factors of TURP
- 1:10 need blood transfusion - Electrolyte problems afer - 5% chance of affecting erections
29
What is HoLep?
Modern laser operation | Better at tissue removal
30
What are the pros of HoLeps
Lesser risk of transfusion, electrolyte probs, erection probs
31
What is a urolift
Newest technique, stapling prostate back
32
What is stress urinary incontinence
Leakage on effort or exersion
33
What is urge incontinence
Leakage accompanied by urgency
34
How does the bladder/ muscles behave in stress incontinence
Cough/ strain | Pressure doesn't go around the bladder as it should but forces bladder down
35
How does bladder/ muscles behave in urge incontinence
No problem with support, but overactive waves | Easy to force urine through and out
36
What conservative measures can be taken to treat urinary problems
Fluid intake Caffeine Pads Timed voiding
37
What are the three main classes of medication for OAB/ urge incontinence
- Anticholinergenics - B3 adrenergenics - Botulum toxin A
38
Give examples of anticholingeric drugs used to treat OAB/ urge incontinence
Oxybutymin Solifenacin Tolterodine Fesoterodine
39
How do anticholinergic drugs work to treat OAB/ urge incontinence
Block acetyl choline in parasympathetic nerves but can also block elsewhere (salivary glands)
40
How do beta adrenergic drugs work
B3 adrenoceptors upregulated in OAB | Hypertension may be an issue
41
How do botulumin toxin A work
Fuses with synaptic vesicles in motor end plate | Issues with hypercontinence
42
Do lesions above the pontine micturition cause problems
No- they are safe
43
Are lesions below T12 safe or unsafe in terms of urination
Bladder doesn't squeeze well but sphincter works so you dribble out- safe
44
In between pontine micturition centre and T12 safe or nto?
UNsafe | Uncooridated so high pressures in the restting bladder