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pharmacology 2 Midterm > midterm 1 pq 2022 > Flashcards

midterm 1 pq 2022 Flashcards

(59 cards)

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1
Q

Amikacin is active against…

A: MRSA
B: Both of them
C: Pasteurella multocida
D: None of them

A

B: Both of them

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2
Q

what is the mechanism of action of lincosamides?

A: Time- dependent bactericidal
B: Inhibition of folic acid synthesis
C: inhibition of protein synthesis
D: cell wall synthesis inhibition

A

C: inhibition of protein synthesis

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3
Q

which agent can be effective against Pseudomonas aeruginosa among the following drug?

A: Tobramycin
B: Amoxicillin with clavulanic acid
C: None of them
D: Spectinomycin

A

A: Tobramycin

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4
Q

which agent can be used in Lawsonia intracellularis infection?

A: Both of them
B: None of them
C: Tylosin
D: Ceftiofur

A

C: Tylosin

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5
Q

inhibition of dihydrofolate- reductase is a ………………… in antimicrobial therapy.

A: None of them
B: Common target
C: Unique target
D: Similar target

A

D: Similar target

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6
Q

Amoxicillin is NOT effective against:

A: Chlamydophila spp
B: Pseudomonas spp
C: Mycoplasma spp
D: None of them

A

D: None of them

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7
Q

Cephalosporins are excreted ….

A: Both of them
B: Via the bile
C: Via the kidney
D: None of them

A

A: Both of them

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8
Q

It has the broadest spectrum from the listed agents:

A: Cefadroxil
B: Cefazolin
C: Cefquinome
D: Cefalexin

A

C: Cefquinome

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9
Q

what is the mechanism of action of aminoglycosides?

A: Cell wall synthesis inhibition
B: Bacteriostatic
C: Inhibition of bacterial cell wall synthesis
D: inhibiton of protein synthesis

A

D: inhibiton of protein synthesis

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10
Q

which bacterium is ab ovo resistant to the beta- lactam antibiotics?

A: Escherichia coli
B: Mycoplasma hyopneumoniae
C: Pseudomonas aeruginosa
D: Staphylococcus aureus

A

B: Mycoplasma hyopneumoniae

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11
Q

what is the mechanism of action of macrolides?

A: inhibition of deoxyribonucleic acid synthesis

B: Inhibition of protein synthesis on the 50S ribosome subunit

C: Concentration dependent bactericidal

D: inhibition of peptidoglycan synthesis

A

B: Inhibition of protein synthesis on the 50S ribosome subunit

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12
Q

Which of the following agents has postantibiotic effect?

A: All of them
B: Piperacillin
C: Phenoxymethylpenicillin
D: Cefalexin

A

A: All of them

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13
Q

which agent would you use in an Escherichia coli UTI ( urinary tract infection)?

A: Amoxicillin
B: Oxacillin
C: Phenoxymethylpenicillin
D: None of them

A

A: Amoxicillin

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14
Q

what is the mode of action of aminoglycosides in general?

A: Concentration - dependent bactericidal

B: Time - dependent bactericidal

C: inhibition of protein synthesis on the 50S ribosome subunit

D: None of these

A

A: Concentration - dependent bactericidal

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15
Q

Piperacillin is NOT effective against:

A: Both of them
B: Mycoplasma spp
C: Pseudomonas spp
D: None of them

A

B: Mycoplasma spp

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16
Q

Cefalexin belongs to the ….

A: 1st generation cephalosporins
B: 4th generation cephalosporins
C: 2nd generation cephalosporins
D: 3rd generation cephalosporins

A

A: 1st generation cephalosporins

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17
Q

which statement is NOT true for chloramphenicol?

A: It can cause dose- independent aplastic anaemia
B: It cannot be given to food- producing animals
C: it can be used topically in ophthalmic products
D: It is effectively used in sheep foot rot

A

D: It is effectively used in sheep foot rot

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18
Q

Which cephalosporin has pronounced elimination via the bile as well?

A: Cefuroxime
B: Cefalexin
C: None of the answers is correct
D: None of any cephalosporins eliminated via the bile, because they are only eliminated via the urine

A

C: None of the answers is correct

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19
Q

Which combination can lead to antagonistic effect?

A: All of them
B: Tylosin + valnemulin
C: Amikacin + metronidazole
D: Lincomycin + spectinomycin

A

B: Tylosin + valnemulin

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20
Q

which combination can lead to additive effect?

A: All of them
B: Tylosin + tulathromycin
C: Ceftiofur + tulathromycin
D: Metronidazole + gentamicin

A

D: Metronidazole + gentamicin

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21
Q

Lincomycin can be used in….

A: Mycoplasmosis in poultry
B: None of them
C: Both of them
D: Strangles in horses

A

A: Mycoplasmosis in poultry

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22
Q

Doxycycline can be effective against:

A: Borellia burgdorferi
B: Anaplasma phagocytophilum
C: Mycoplasma haemofelis
D: All of them

A

D: All of them

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23
Q

Which agent can be used in Lawsonia intracellularis infection?

A: Ceftiofur
B: Tylosin
C: None of them
D: Both of them

A

B: Tylosin

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24
Q

which substance belongs to CIA Highest Priority (AMEG B) of antibiotics category?

A: Lincomycin
B: Streptomycin
C: Cefuroxime
D: Colistin

25
if a Pseudomonas aeruginosa strain is resistant to gentamicin, the following agent can still be effective: A: Neomycin B: Amikacin C: Streptomycin D: None of them can be effective, they are all aminoglycosides
B: Amikacin
26
Clindamycin can be used in... A: oral cavity infections B: All of them C: Osteomyelitis D: Anal sacculitis
A: oral cavity infections
27
What is the mode of action of lincosamides? A: time - dependent bactericidal B: None of these C: concentration - dependent bactericidal D: Bacteriostatic
D: Bacteriostatic
28
which agent can be used in lawsomnia intracellularis infection? A: Tiamulin B: Lincomycin C: None of them D: Both of them
D: Both of them
29
which aminoglycosides is the safest among the following? A: Spectinomycin B: Streptomycin C: Tobramycin D: Neomycin
A: Spectinomycin
30
which is NOT true for cefalexin? A: it is concentration - dependent bactericidal B: it is a first - generation cephalosporin C: it has postantibiotic effect D: it is not inactivated by beta- lactamase producing staphylococcus pseudointermedius
A: it is concentration - dependent bactericidal
31
it has the broadest spectrum from the listed agents: A: Cefazolin B: Cefadroxil C: Cefakexin D: Cefquinome
D: Cefquinome
32
select the correct answer! aminoglycosides body distribution is generally .... A: Poor, they can barely cross the special barriers B: Excellent, they can cross both the special barriers and the cell membrane C: Poor, they are quickly eliminated from the body even if they are given in injections D: Good, they can barely enter the cells, but they can cross the blood - milk barrier
A: Poor, they can barely cross the special barriers
33
most effective in bacterial meningitis from the listed agents A: Cefovecin B: Ceftriaxone C: Pivampicillin D: Amoxicillin + clavulanic acid
B: Ceftriaxone
34
what is the mode of action of pleuromutilins? A: Concentration - dependent bactericidal B: None of these C: bacteriostatic D: Time - dependent bactericidal
C: bacteriostatic
35
which agent(s) would you use in a Pseudomonas aeruginosa infection? A: Piperacillin + tazobactam B: none of them C: flucloxacillin D: Amoxicillin + clavulanic acid
A: Piperacillin + tazobactam
36
what is the mechanism of action of lincosamides? A: inhibition of protein synthesis on the 50S B: inhibition of protein synthesis on the 30S ribosome subunit C: innhibition of peptidoglycan synthesis D: inhibition of deoxyribonucleic acid synthesis
A: inhibition of protein synthesis on the 50S
37
There´s NO glycoside bond in the structure of this antibiotic: A: Spectinomycin B: Streptomycin C: Amikacin D: All of them have glycoside bonds
A: Spectinomycin
38
Doxycycline can be effective against: A: both of them B: Bordetella bronchiseptica C: Escherichia coli D: None of them
A: both of them
39
which statement is true for tetracyclines? A: They are highly active antibiotics resistance is rare B: Divalent cations decrease their oral bioavailability C: They have direct anthelminthic activity D: They have wide spectrum of activity, but mycoplasma spp are ab ovo resistant
B: Divalent cations decrease their oral bioavailability
40
which cephalosporin has pronounced elimination via the bile as well? A: Cefuroxime B: None of any cephalosporins eliminated via the bile, because they are eliminated via the urine C: None of these answers is correct D: Cefalexin
C: None of these answers is correct
41
which agent can be used in Lawsonia intracellularis infection? A: None of them B: Ceftiofur C: Both of them D: Tylosin
D: Tylosin
42
which substance belongs to CIA Highest Priority (AMEG B) category? A: Streptomycin B: Cefuroxime C: Colistin D: Lincomycin
C: Colistin
43
Neomycin is active against..... A: None of them B: Clostridium perfringens C: Fusobacterium necrophorum D: Both of them
A: None of them
44
Inhibition of cell wall synthesis is.... A: Unique target B: Similar target C: None of them D: Common target
A: Unique target
45
What is the mode of action of pleuromutilins? A: Bacteriostatic B: Time-dependent bactericidal C: Concentration-dependent bactericidal D: Agent-dependent bactericidal
A: Bacteriostatic
46
Which agent can be given IV? A: Amoxicillin trihydrate B: Benzathine benzylpenicillin C: Procaine benzylpenicillin D: Benzylpenicillin sodium
C: Procaine benzylpenicillin
47
Which combination can lead to decreased efficacy? A: Colistin + amoxicillin B: Amoxicillin + clavulanic acid C: Phenoxymethylpenicillin + florfenicol D: Doxycycline + tulathromycin
C: Phenoxymethylpenicillin + florfenicol
48
Which substance belongs to the CIA Highest Priority (AMEG B) category? A: Cefapirin B: Ceftiofur C: Cefadroxil D: Cefalexin
B: Ceftiofur
49
Amoxicillin is active against.... A: Pseudomonas spp. B: Chlamydophila spp. C: None of them D: Mycoplasma spp.
C: None of them
50
Cefalexin belongs to the... A: 4th generation cephalosporins B: 1st generation cephalosporins C: 3rd generation cephalosporins D: 2nd generation cephalosporins
B: 1st generation cephalosporins
51
Prevalence of resistance is highest in case of this agent amoung followings: A: Amikacin B: Tobramycin C: Neomycin D: streptomycin
D: streptomycin
52
what is the aim when colistin is used? A: Both should be achieved B: None of them is true C: The drug concentration should be above the MIC as long as possible D: The drug concentration should be above the MIC as much as possible
D: The drug concentration should be above the MIC as much as possible
53
Effective against Pseudomonas aeruginosa: A: Cefoperazon B: Ceftiofur C: Cefovecin D: Cefuroxime
A: Cefoperazon
54
what does MIC stand for? A: Median inhibitory concentration B: Maximum inhibitory concentration C: Minimum inhibitory concentration D: Mean inhibitory concentration
C: Minimum inhibitory concentration
55
Phenicols can be used in.... A: None of them B: Bovine respiratory disease complex C: Both of them D: Aeromonas salmonidae infection
C: Both of them
56
What is the mode of action of tetracyclines? A: Time-dependent bactericidal B: Concentration-dependent bactericidal C: Agent-dependent bactericidal D: Bacteriostatic
D: Bacteriostatic
57
This bacterium usually does not produce beta- lactamase enzymes A: Streptococcus suis B: Staphylococcus aureus C: Pseudomonas aeruginosa D: Escherichia coli
A: Streptococcus suis
58
This side effect is NOT characteristic to phenicols A: Severe kidney damage B: Dose-dependent anaemia C: Tissue irritation D: Immunosuppression
A: Severe kidney damage
59
Which combination can lead to antagonistic effect? A: All of them B: Metronidazole + gentamicin C: Tetracycline + tulathromycin D: Ceftiofur + doxycycline
D: Ceftiofur + doxycycline

pharmacology 2 Midterm (5 decks)

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