MISCELLANEOUS ENZYMES

Question 1

5’ NUCLEOTIDASE (5’N) systematic name

Answer 1

Phosphoric Monoester Hydrolase

Question 2

5’ NUCLEOTIDASE (5’N) predominantly secreted in the _____

Answer 2

LIVER

Question 3

5’ NUCLEOTIDASE (5’N) is marker for ___ & ____ of the liver

Answer 3

hepatobiliary disease & infiltrative lesions

Question 4

5’ NUCLEOTIDASE (5’N) is marker for ___ & ____ of the liver

Answer 4

hepatobiliary disease & infiltrative lesions

Question 5

5’ NUCLEOTIDASE (5’N) reference value

Answer 5

0-1.6 units

Question 6

Index of parenchymal function

Answer 6

CHOLINESTERASE/ PSEUDOCHOLINESTERASE

Question 7

Monitors effect of muscle relaxants (succinylcholine) after surgery

Answer 7

CHOLINESTERASE/ PSEUDOCHOLINESTERASE

Question 8

CHOLINESTERASE/ PSEUDOCHOLINESTERASE is used as marker for

Answer 8

insecticide/ pesticide/
poisoning (organophosphate component)

Question 9

CHOLINESTERASE/ PSEUDOCHOLINESTERASE reference value

Answer 9

0.5-1.3 units in the plasma

Question 10

ANGIOTENSIN-CONVERTING ENZYME (ACE) is also known as

Answer 10

Peptidyldipeptidase A or Kininase II

Question 11

ANGIOTENSIN-CONVERTING ENZYME (ACE) is useful for converting _____ (inactive form) to ____ (active form) in the _____

Answer 11

Angiotensin I
Angiotensin II
LUNGS

Question 12

ACE is also a possible indicator of neuronal dysfunction ______ important for the diagnosis of ____

Answer 12

dementia
Alzheimer’s

Question 13

ACE is increased in

Answer 13

○ Sarcoidosis
○ Acute and chronic bronchitis
○ Leprosy

Question 14

ANGIOTENSIN-CONVERTING ENZYME (ACE) main source

Answer 14

Macrophage & Epithelioid cells; found in the lungs

Question 15

A copper-carrying protein which acts as an enzyme

Answer 15

CERULOPLASMIN

Question 16

CERULOPLASMIN is marker for

Answer 16

Wilson’s Disease (hepatolenticular disease)

Question 17

Ceruloplasmin is ___ in Wilson’ disease.

Answer 17

low

Question 18

For hepatobiliary diseases.

Answer 18

ORNITHINE CARBAMOYL TRANSFERASE (OCT)

Question 19

ORNITHINE CARBAMOYL TRANSFERASE (OCT) reference value

Answer 19

8-20 mU/mL

Question 20

It functions to maintain NADPH in the reduced form in the erythrocytes.

Answer 20

GLUCOSE-6-PHOSPHATE DEHYDROGENASE (G6PD)

Question 21

____ serves as a protective coenzyme

Answer 21

NADPH

Question 22

A newborn screening marker

Answer 22

GLUCOSE-6-PHOSPHATE DEHYDROGENASE (G6PD)

Question 23

GLUCOSE-6-PHOSPHATE DEHYDROGENASE (G6PD) is found in

Answer 23

adrenal cortex, spleen, RBC, and lymph nodes.

Question 24

DECREASED G-6-PD or Deficiency can lead to ________

Answer 24

drug-induced hemolytic anemia

Question 25

ONLY enzyme that is significant when decreased

Answer 25

GLUCOSE-6-PHOSPHATE DEHYDROGENASE (G6PD)

Question 26

GLUCOSE-6-PHOSPHATE DEHYDROGENASE (G6PD) increased levels

Answer 26

* Myocardial infarction * Megaloblastic anemia

Question 27

G6PD specimen

Answer 27

* Red Cell Hemolysate * Serum

Question 28

G6PD reference value

Answer 28

10-15 U/g Hgb/1200-2000 mU/mL packed RBC

Question 29

Liver Enzymes

Answer 29

Transaminases Transpeptidase Phosphatases Miscellaneous

Question 30

Transaminases Transpeptidase Phosphatases Miscellaneous

Answer 30

Transaminases - ALT, AST Transpeptidase - GGT Phosphatases - ALP, ACP Miscellaneous - 5'NT

Question 31

CARDIAC ENZYMES

Answer 31

CK, AST, LDH

Question 32

PANCREATIC ENZYMES

Answer 32

Amylase & Lipase

Question 33

OTHER MISCELLANEOUS ENZYMES

Answer 33

Cholinesterase, ACE, Ceruloplasmin, OCT, & G-6-PD