mixed deck 04/08 Flashcards Preview

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Flashcards in mixed deck 04/08 Deck (11):

Atrial natriuretic peptide

-ANP dilates AFFERENT arterioles increasing the glomerular filtration rate and the urinary excretion of sodium and water. it also limits Na reabsorption in the PT and inhibits renin secretion

Adrenal gland:
ANP restricrits aldosterone secretion

Blood vessels:
ANP relaxes smooth muscle


volatile anesthetics

increase cerebral blood flow


drug metabolized by first order kinetics, to reach stready state

the steady state concentration is reached in 4-5 half lives, 95%


most effective agents for the treament of hypertriglyceridemia?

niacin and fibrates


insulin secretion

para and sympathetic nerves innervate the beta islet cells of the pancrease
-parasympathetic activation is respinsible for insulin secretion and is induced by the smell or sight of food.
-stimulate alpha receptor inhibit insulin
-stimulate beta receptors stimulate insulin sectretion
-phenoxybenzamine is a long acting alpha blocker

since epi can bind to both alpha and beta, use an alpha blocker to allow more epi to bind to beta receptor and reults in an increase in insulin secretion


juvenile hemangiomas

intially grow grow then regress usually by 7


Tricyclic antidepressants toxicity

they have a quinidine like effect (class 1a) on the cardiac conduction system, potentially causing QRS and QT prolongation and cardiac dysrhythmias. These effects are due to inhibiton of fast sodium channels.

in a cardio toxicity due to TCA overdose treat with NaHCO3 to correct the QRS prolongation, reverse hypotension and treat the ventricular dysrhythmia


cerebral vascular spasm following SAH

calcium channel blocker nimodipine



is most often caused by defects in mitral valve CONNECTIVE TISSUE proteins that predispose to myxomatous degerenation


Linezolid used to treat gram positive bacteria VRE and MRSA butttttt watch out! its a weak MAO inhibitor

seretonin syndrome!
1. neuromuscular excitation:hyperflexia, clonus, myoclonus, rigidity
2. autonomic stimulation:hyperthermia, tachycardia, diaphoresis and tremor
3. altered mental status: agitation and confusion



xanthoma usually found on the medial eyelids
-hyperlipidemia or dyslipidemia