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Pharmacology > MOA: Gastrointestinal and Antiemetic Drugs > Flashcards

MOA: Gastrointestinal and Antiemetic Drugs Flashcards

(55 cards)

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1
Q

Amoxicillin

A

Used to Treat Acid-Peptic Diseases
Antimicrobial Agents

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2
Q

Bismuth compounds

A

Used to Treat Acid-Peptic Diseases
Antimicrobial Agents

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3
Q

Clarithromycyin

A

Used to Treat Acid-Peptic Diseases
Antimicrobial Agents

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4
Q

Metronidazole

A

Used to Treat Acid-Peptic Diseases
Antimicrobial Agents

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5
Q

Tetracycline

A

Used to Treat Acid-Peptic Diseases
Antimicrobial Agents

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6
Q

Cimetidine

A

Used to Treat Acid-Peptic Diseases

H2-Receptor Blockers
Competitively block the binding of histamine

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7
Q

Famotidine

A

Used to Treat Acid-Peptic Diseases

H2-Receptor Blockers
Competitively block the binding of histamine

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8
Q

Nizatidine

A

Used to Treat Acid-Peptic Diseases

H2-Receptor Blockers
Competitively block the binding of histamine

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9
Q

Ranitidine

A

Used to Treat Acid-Peptic Diseases

H2-Receptor Blockers
Competitively block the binding of histamine

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10
Q

Dexlansoprazole

A

Used to Treat Acid-Peptic Diseases
Proton Pump Inhibitors (PPIs)

Bind to the proton pump and prevent secretion of hydrogen ions

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11
Q

Esomeprazole

A

Used to Treat Acid-Peptic Diseases
Proton Pump Inhibitors (PPIs)

Bind to the proton pump and prevent secretion of hydrogen ions

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12
Q

Lansoprazole

A

Used to Treat Acid-Peptic Diseases
Proton Pump Inhibitors (PPIs)

Bind to the proton pump and prevent secretion of hydrogen ions

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13
Q

Omeprazole

A

Used to Treat Acid-Peptic Diseases
Proton Pump Inhibitors (PPIs)

Bind to the proton pump and prevent secretion of hydrogen ions

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14
Q

Pantoprazole

A

Used to Treat Acid-Peptic Diseases
Proton Pump Inhibitors (PPIs)

Bind to the proton pump and prevent secretion of hydrogen ions

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15
Q

Rabeprazole

A

Used to Treat Acid-Peptic Diseases
Proton Pump Inhibitors (PPIs)

Bind to the proton pump and prevent secretion of hydrogen ions

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16
Q

Misoprostol

A

Used to Treat Acid-Peptic Diseases
Prostaglandins
Inhibits secretion of HCl and stimulates secretion of mucus and bicarbonate – protective factors

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17
Q

Dicyclomine

A

Used to Treat Acid-Peptic Diseases
Antimuscarinic Agents
ACh receptor blocker

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18
Q

Aluminum hydroxide

A

Used to Treat Acid-Peptic Diseases
Antacid
Weak bases that react with gastric acid and neutralize it to form water and salt

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19
Q

Calcium carbonate

A

Used to Treat Acid-Peptic Diseases
Antacid
Weak bases that react with gastric acid and neutralize it to form water and salt

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20
Q

Magnesium hydroxide

A

Used to Treat Acid-Peptic Diseases
Antacid
Weak bases that react with gastric acid and neutralize it to form water and salt

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21
Q

Sodium bicarbonate

A

Used to Treat Acid-Peptic Diseases
Antacid
Weak bases that react with gastric acid and neutralize it to form water and salt

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22
Q

Bismuth subsalicyclate

A

Used to Treat Acid-Peptic Diseases
Mucosal Protective Agents

Antimicrobial action, inhibits pepsin activity, increases mucous secretion, coats/protects ulcer craters

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23
Q

Sucralfate

Study These Flashcards
A

Used to Treat Acid-Peptic Diseases
Mucosal Protective Agents

Forms complex gel with epithelial cells and covers area of injury. Also stimulates prostaglandin secretion

24
Q

Prochlorperazine

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A

Used to Treat Chemotherapy-Induced Nausea
Phenothiazines
Block dopamine, histamine, and muscarinic receptors in the CTZ

25
Promethazine
Used to Treat Chemotherapy-Induced Nausea Phenothiazines Block dopamine, histamine, and muscarinic receptors in the CTZ
26
Droperidol
Used to Treat Chemotherapy-Induced Nausea Butyrophenones Blocks dopamine receptors
27
Haloperidol
Used to Treat Chemotherapy-Induced Nausea Butyrophenones Blocks dopamine receptors
28
Metoclopramide
Used to Treat Chemotherapy-Induced Nausea Substituted Benzamide Blocks dopamine receptor
29
Alprazolam
Used to treat chemotherapy-induced nausea Benzodiazepine Binding enhances inhibitory effects of GABA -- sedative effects help against psychological nausea
30
Lorazepam
Used to treat chemotherapy-induced nausea Benzodiazepine Binding enhances inhibitory effects of GABA -- sedative effects help against psychological nausea
31
Dolasetron
Used to treat chemotherapy-induced nausea 5-HT3 Receptor blockers Antagonists at serotonin receptors, specifically 5-HT3 receptors
32
Granisetron
Used to treat chemotherapy-induced nausea 5-HT3 Receptor blockers Antagonists at serotonin receptors, specifically 5-HT3 receptors
33
Ondansetron
Used to treat chemotherapy-induced nausea 5-HT3 Receptor blockers Antagonists at serotonin receptors, specifically 5-HT3 receptors
34
Palonosetron
Used to treat chemotherapy-induced nausea 5-HT3 Receptor blockers Antagonists at serotonin receptors, specifically 5-HT3 receptors
35
Dexamethasone
Used to treat chemotherapy-induced nausea Corticosteroids may involve blockade of prostaglandins
36
Methylprednisone
Used to treat chemotherapy-induced nausea Corticosteroids may involve blockade of prostaglandins
37
Aprepitant
Used to treat chemotherapy-induced nausea Substance P/Neurokinin-1 Receptor Blocker Targets and blocks the neurokinin receptors in the CTZ
38
Diphenoxylate + atropine
Drugs to treat Diarrhea Antimotility agents Opioid-like actions in the gut; inhibit ACh release and decrease peristalsis
39
Loperamide
Drugs to treat Diarrhea Antimotility agents Opioid-like actions in the gut; inhibit ACh release and decrease peristalsis
40
Aluminum hydroxide
Drugs to treat Diarrhea Adsorbents Adsorb intestinal toxins that are causing problems and also coat the intestinal mucosa to provide protection
41
Methylcellulose
Drugs to treat Diarrhea Adsorbents Adsorb intestinal toxins that are causing problems and also coat the intestinal mucosa to provide protection
42
Bismuth Subsalicylate (pepto bismol)
Drugs to treat Diarrhea Agents that Modify Fluid and Electrolyte Transport Decreases fluid secretion
43
Bisacodyl
Drugs to treat constipation Stimulants Stimulants cause evacuation of bowels and water/electrolyte secretion
44
Senna
Drugs to treat constipation Stimulants Stimulants cause evacuation of bowels and water/electrolyte secretion
45
Castor oil
Drugs to treat constipation Irritant Irritates the stomach and initiates peristalsis
46
Methylcellulose
Drugs to treat constipation Bulk-Laxatives Form gels in the large intestine, causing water retention and intestinal distention
47
Psyllium
Drugs to treat constipation Bulk-Laxatives Form gels in the large intestine, causing water retention and intestinal distention
48
Magnesium citrate
Drugs to treat constipation Saline and Osmotic Laxatives Nonabsorbable salts or electrolytes that hold water in the intestine by osmosis
49
Magnesium hydroxide
Drugs to treat constipation Saline and Osmotic Laxatives Nonabsorbable salts or electrolytes that hold water in the intestine by osmosis
50
Polyethylene glycol
Drugs to treat constipation Saline and Osmotic Laxatives Nonabsorbable salts or electrolytes that hold water in the intestine by osmosis
51
Lactulose
Drugs to treat constipation Saline and Osmotic Laxatives Nonabsorbable salts or electrolytes that hold water in the intestine by osmosis
52
Docusate
Drugs to treat constipation Stool softeners Emollients and surfactants; may be used more for prevention of constipation rather than treatment
53
Glycerin suppositories
Drugs to treat constipation Lubricant laxatives Mineral oil and glycerin suppositories that provide lubrication
54
Mineral oil
Drugs to treat constipation Lubricant laxatives Mineral oil and glycerin suppositories that provide lubrication
55
Lubiprostone
Drugs to treat constipation Chloride channel activators Activate chloride channels and increase fluid secretion into the intestinal lumen

Pharmacology (34 decks)

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