mock test

Question 1

Mock Exam — Applied Bioscience 📝
Multiple Choice Questions (13 questions, 1 min each) ⏳

1. What is the primary organ responsible for drug metabolism? 🏭
   A) Kidney 🚽
   B) Liver 🍷
   C) Heart ❤️
   D) Lungs 🌬️
2. Which process describes the movement of a drug from the bloodstream into tissues? 🚀
   A) Absorption 🌡️
   B) Distribution 🩸
   C) Metabolism 🔄
   D) Excretion 🚽
3. A receptor antagonist:
   A) Activates the receptor ⚡
   B) Blocks the receptor 🚫
   C) Enhances the drug effect 🔥
   D) Degrades the drug 💥
4. What does the therapeutic index ⚖️ indicate?
   A) Drug’s potency
   B) Drug safety margin
   C) Drug absorption rate
   D) Drug half-life
5. Which of the following drugs is commonly used as a beta-2 agonist in asthma? 💨
   A) Salbutamol
   B) Prednisolone
   C) Atropine
   D) Morphine
6. What is bioavailability? 🎯
   A) Time taken for drug elimination
   B) Proportion of drug reaching systemic circulation
   C) Drug’s half-life
   D) Site of drug metabolism
7. What does the half-life of a drug represent? ⏳
   A) Time to reach peak effect
   B) Time to eliminate 50% of the drug
   C) Time before the drug is absorbed
   D) Time for drug to bind receptor
8. In asthma, bronchoconstriction occurs because of:
   A) Excess mucus secretion
   B) Airway smooth muscle contraction 💪
   C) Alveolar collapse
   D) Lung fibrosis
9. Corticosteroids reduce asthma symptoms mainly by:
   A) Relaxing airway muscles
   B) Reducing inflammation 🔥
   C) Dilating blood vessels
   D) Increasing mucus secretion
10. Which process eliminates drugs primarily via urine? 🚽
    A) Absorption
    B) Distribution
    C) Metabolism
    D) Excretion
11. A partial agonist:
    A) Fully activates the receptor
    B) Blocks the receptor
    C) Produces a weaker response than a full agonist 🌓
    D) Inhibits enzyme activity
12. Which of these factors affects drug absorption? 🌍
    A) pH level ⚗️
    B) Blood flow 💉
    C) Surface area 📐
    D) All of the above ✔️
13. Which test is commonly used to diagnose asthma? 🩺
    A) Spirometry
    B) ECG
    C) Blood glucose
    D) MRI

Answer 1

B) Liver 🍷 — Primary organ for drug metabolism

B) Distribution 🩸 — Movement of drug from bloodstream into tissues

B) Blocks the receptor 🚫 — Receptor antagonist blocks receptor

B) Drug safety margin ⚖️ — Therapeutic index indicates safety margin

A) Salbutamol 💨 — Common beta-2 agonist for asthma

B) Proportion of drug reaching systemic circulation 🎯 — Bioavailability

B) Time to eliminate 50% of the drug ⏳ — Drug half-life

B) Airway smooth muscle contraction 💪 — Cause of bronchoconstriction in asthma

B) Reducing inflammation 🔥 — Corticosteroids reduce asthma symptoms by this

D) Excretion 🚽 — Drugs eliminated mainly via urine

C) Produces a weaker response than a full agonist 🌓 — Partial agonist

D) All of the above ✔️ — pH, blood flow, surface area all affect absorption

A) Spirometry 🩺 — Common diagnostic test for asthma

Question 2

Fill in the Missing Word (2 questions, 5 min each) ✍️
Word Bank:
A) constriction
B) dilation
C) inflammation
D) infection
E) swallowing
F) breathing
G) digesting
H) seeing
I) contraction
J) relaxation
K) fibrosis
L) swelling

Paragraph:
Asthma is a chronic respiratory condition characterized by airway _______ (1) and increased mucus production. This leads to symptoms such as wheezing, coughing, and difficulty _______ (2). Beta-2 agonists work by causing _______ (3) of the airway smooth muscles, which helps to open the airways. Corticosteroids reduce airway _______ (4) by inhibiting inflammatory mediators.

Answer 2

Asthma is a chronic respiratory condition characterized by airway A) constriction (1) and increased mucus production. This leads to symptoms such as wheezing, coughing, and difficulty F) breathing (2). Beta-2 agonists work by causing J) relaxation (3) of the airway smooth muscles, which helps to open the airways. Corticosteroids reduce airway C) inflammation (4) by inhibiting inflammatory mediators.

Question 3

Short Paragraph Response (1 question, max 200 words, 7 min) 📝
16. Briefly explain the pathophysiology of asthma and describe the mechanisms of action of beta-2 agonists and corticosteroids used in its treatment.

Answer 3

Ideal Short Paragraph Answer ✅
Asthma is a chronic inflammatory disease characterized by airway inflammation, bronchoconstriction, and increased mucus production. The inflammation causes hypersensitivity of airway smooth muscles, leading to narrowing of the airways and difficulty breathing. Beta-2 agonists, such as salbutamol, work by stimulating beta-2 adrenergic receptors on airway smooth muscle, causing relaxation and bronchodilation, which opens the airways and improves airflow. Corticosteroids reduce airway inflammation by inhibiting the release of inflammatory mediators and suppressing immune cell activity, thereby decreasing swelling and mucus production. Together, these drugs help relieve symptoms and improve lung function in asthma patients.