Q: What are the four main types of drug-receptor interactions? 🤔 Flashcards
(9 cards)
Q: What are the four main types of drug-receptor interactions? 🤔
A: Agonists ⚡, antagonists 🚫, partial agonists 🌓, and inverse agonists 🔄.
Q: What is the dose-response curve? 📈
A: A graph showing the relationship between the drug dose 💊 and the magnitude of the drug’s effect.
Q: Define therapeutic index. ⚖️
A: The ratio between the toxic dose ☠️ and the therapeutic dose ✅ of a drug; indicates drug safety.
Q: What is the difference between efficacy and potency? 💪 vs 🔥
A: Efficacy is the maximum effect a drug can produce 🏆; potency is the amount of drug needed to produce a given effect 🎯.
Pharmacokinetics – General Principles
Q: What are the four main processes of pharmacokinetics? 🚀
A: Absorption 🌡️, distribution 🩸, metabolism 🏭, and excretion 🚽 (ADME).
Q: What factors can affect drug absorption? 🌍
A: Route of administration 🚪, blood flow 💉, surface area 📐, solubility 💧, and pH ⚗️.
Q: What is bioavailability? 🎯
A: The proportion of a drug that enters the systemic circulation and is available to have an active effect.
Q: What organ is primarily responsible for drug metabolism? 🏭
A: The liver 🍷.
Q: What is the significance of the half-life of a drug? ⏳
A: The time it takes for the plasma concentration of a drug to reduce by half; guides dosing intervals.
