moclobemide (Aurorix)

Question 1

Class

Answer 1

MAOI

Question 2

Indications

Answer 2

• Major depression
• Panic disorder
• Social phobia

2nd best after mirtazepine for sexual dysfunction

Question 3

Dose Range

Answer 3

300 – 600mg d in 1-2 divided doses

Question 4

Counseling/SE

Answer 4

• Moclobemide is best taken with, or soon after, food.
• Take doses no later than early afternoon or you may have trouble sleeping at night.
• Although moclobemide is unlikely to affect your ability to drive or operate machinery, be careful with these types of tasks until you know how you are affected.
• if you have any thoughts of harming yourself then let the doctor know.

SE:

• dry mouth
• constipation
• anxiety
• agitation
• insomnia
• dizziness, headache
• GI upset (n, v, feeling of fullness)
• visual disturbances

Question 5

Monitoring

Answer 5

• psych review (compliance, tolerability & worsening of condition)
• behaviour (increase suicidal thoughts)