Mod 3 CNS Stimulants and Related Drugs Flashcards Preview

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Flashcards in Mod 3 CNS Stimulants and Related Drugs Deck (7):
1

Stimulants

Drugs that stimulate specific areas of the
brain or spinal cord
Slide 2
 Sympathomimetic drugs

2

CNS Stimulants: Uses

Analeptics (CNS stimulants)
 Appetite suppressants (anorexiant)
 Treatment of
Slide 3
 Attention deficit hyperactivity disorder (ADHD)
 Narcolepsy
 Migraine headaches

3

CNS Stimulants: Indications

ADHD
 Stimulate areas in the brain responsible for mental
alertness and attentiveness
Slide 4
 Anorexiant
 Suppress appetite control center in the brain
 Analeptic
 Neonatal apnea, bronchopulmonary dysplasia,
postanesthetic respiratory depression
Narcolepsy
 Increase mental alertness
Mi i h d h
Slide 5
 Migraine headaches
 Caffeine, co-administered with other drugs, used
to treat headaches

4

Adverse Effects

Tend to “speed up” body systems
 Common adverse effects include:
Slide 6
 Palpitations, tachycardia, hypertension, angina,
dysrhythmias, nervousness, restlessness, anxiety,
insomnia, nausea, vomiting, diarrhea, dry mouth,
increased urinary frequency

5

CNS Stimulants

ADHD
 amphetamine (Adderall)
 methylphenidate (Concerta, Ritalin)
Slide 7
 atomoxetine (Strattera)
• Nonaddictive
• May cause suicidal thinking and behavior
 Narcolepsy
 modafinil (Provigil)
Anorexiants
 sibutramine (Meridia)
 phentermine ( Lonamin)
Slide 8
p )
 orlistat (Xenical)
• Lipase inhibitor, not a CNS stimulant
• Also used to treat obesity
• May cause fecal incontinence

6

CNS Stimulants (cont’d)

Antimigraine (serotonin agonists)
 almotriptan (Axert)
 eletriptan (Relpax)
f i (F )
Slide 9
 frovatriptan Frova)
 naratriptan (Amerge)
 rizatriptan (Maxalt)
 sumatriptan (Imitrex)
 zolmitriptan (Zomig)
Analeptics
 Used less frequently
 Still used for neonatal apnea
Slide 10
 Examples:
• doxapram (Dopram)
• Methylxanthines, such as aminophylline, theophylline,
and caffeine

7

CNS Stimulants (cont’d)

Caffeine
 Found in:
• Over-the-counter drugs
• Combination prescription drugs
Slide 11
• Foods and beverages
 Use with caution in patients with a history of:
• Peptic ulcer
• Recent myocardial infarction
• Dysrhythmias
Caffeine (cont’d)
 Many uses
N t l
Slide 12
• Neonatal apnea
• Respiratory depression in adults
• Enhances effects of analgesics and migraine
medications
• Stimulates CNS (NoDoz, Vivarin)