Module 2 & 3 Flashcards
(17 cards)
what is the diagnostic tool for VTE in preg?
compression US
what are the causes of PPH?
trauma, tone, tissue, thrombin, lac
what immune cell is most abundant in uterus in early preg?
uNK
which hormone increases TBG in preg?
estrogen
what immune shift occurs in pregnancy?
TH2 dominance
what is a CI to codeine in BF?
ultrarapid metabolism risk
what is the safe relative infant dose?
<10%
how is AFLP initially diagnosed?
LFTs for alkaline phosphatase
what condition in pregnancy assoc w pruritus and elevated bile acids?
ICP
what is the most common symptom of HELLP syndrome?
RUQ pain
what are the primary concerns of using valproate in preg?
NTDs, neurodevelopmental disorders
describe MOA paracetamol
may inhibit COX3 in CNS, provides analgesic and antipyretic effects
describe physiological changes in GIT in preg contributing to N and V
prog causes smooth muscle relaxation which causes delayed gastric emptying and slows intestinal transit, hCG assoc w nausea due to impacts on TH
describe diagnosis and management of ICP
pruritus without rash (hands and feet), elevated bile acids and transaminases, manage with UDCA
list mat and fetal risks of HELLP syndrome
mat: liver/renal failure, DIC, stroke, seizure, haemorrhage
fetal: plac abruption, IUGR, stillbirth, premature
describe effects of poorly controlled asthma on female and male fetuses
female: will become small to better cope with reduced O2 supply
male: will cont growing as normal therefore increased risk IUGR, stillbirth, preterm since not prepared for low O2 conditions
describe effects of mat stress/anx on fetal development
early exposure to cortisol can cause GR, poor immunity, altered brain dev, increased risk of adult diseases, preterm, stillbirth
