Module 2C: Neuroanatomy Of The Digestive System Flashcards
(83 cards)
Recall that Σ and РΣ function as unconscious motor neurons, all are classified
as ___ neurons / axons.
GVE
There are the two autonomic motor system neurons required from the spinal
cord / brainstem to the effector:
these are called the pre- and post-ganglionic
neurons.
The Σ system has an endocrine homologue in the _________ ________, the РΣ system does not.
adrenal medulla
Adrenal medulla releases?
Epinephrine
Sympathetic Functions
-reactions to stress
-Increased heart function; bronchodilation, decreased mucous secretion; decreased digestive function (decreased peristalsis, constriction of sphincters; pupillary dilation; vasodilation in vessels of skeletal muscle, vasoconstriction in other vessels; allows bladder filling; ejaculation
Parasympathetic Functions
-recovery of rest, vegetative functions
-Decreased heart function; bronchoconstriction and increased mucous secretion; increased digestion (increased peristalsis, glandular secretion, opening of sphincters); pupillary constriction, specific vasodilation in salivary glands, GI vessels, and erectile tissues; managing bowel and bladder emptying
Innervation of the Abdominopelvic Viscera: General Information
Sympathetic Preganglionic Origins
Intermediolateral Nucleus (IML) T6-L2
Parasympathetic Preganglionic Origins:
Dorsal Motor Nucleus of X (DMX) to
the transverse colon, distal to that: Sacral Parasympathetic Nucleus (SPN) of S2
-4.
The preganglionic sympathetic synapse is NOT in the chain, but in the pre-
_________ _______associated with the abdominal aorta . These prevertebral
ganglia have names (see the next page)
Vertebral ganglia
The _____________ parasympathetic cell bodies are IN the organ (intramural)
Postganglionic
Innervation of the Abdominopelvic Viscera: Splanchnic Nerves and Prevertebral Ganglia
• Sympathetic Splanchnic Nerves
• Greater splanchnic nerve: T6-9 —> celiac ganglion
• Lesser splanchnic nerve: T10-11 —> superior mesenteric ganglion
• Least splanchnic nerve: T12 —> inferior mesenteric ganglion
• Lumbar splanchnic nerves: L1-2 —> inferior hypogastric ganglion
• Sacral splanchnic nerves: L1-2 —> inferior hypogastric ganglion
Innervation of the Lower Gut, Bladder
• Parasympathetic Splanchnic Nerves
• Pelvic splanchnic nerve: S2-4 pelvic ganglion l (aka
inferior hypogastric ganglion) • The Vagus nerve innervation ends at the transverse
colon… the descending colon, sigmoid colon, rectum,
bladder and reproductive organs receive their
parasympathetic input from the sacral cord… the SPN S2-
4 from which are derived the PELVIC splanchnic nerves.
Autonomic Function in the Abdominopelvic Cavity
Sympathetic input slows or stops digestion and digestive activity
• Inhibitory to glandular secretion and peristalsis: NE, beta-2 (β-2)
• Excitatory to sphincter activity: NE, Alpha-1 (α-1)
• Vasoconstrictive to redirect blood to the brain, heart, and extremities: NE
Autonomic Function in the Abdominopelvic Cavity
Parasympathetic input enhances and supports digestion
• Excitatory to glandular secretion and peristalsis: ACh, M1/3 +
• Inhibitory to sphincter activity: Ach, M3 -
• As usual, there is little ƤƩ effect on vascular smooth muscle
Innervation of the stomach
Sympathetic pathway
Pre gel CB origin:
Pre ggl path:
Post ggl CB origin:
Post ggl path:
Preganglionic CB Origin: T6-T9
Preganglionic Path: Enter white rami—> THROUGH sympathetic chain to become the Greater splanchnic nerve
Postganglionic CB Origin: Celiac Pleus and Ganglion
Postganglionic Path: 1. Left gastric plexus
2. Splenic plexus to short gastric plexus
3. Splenic plexus to left gastroepiplioc plexus
4. Common hepatic to gfastroduodenal to right gastroepiplic plexus
5. Common hepatic to proper hepatic to right gastric plexus —> sympathetic GI function
Innervation of the stomach
Parasympathetic pathway:
Pre ggl CB origin:
Pre ggl path:
Post ggl CB origin:
Post ggl path:
Preganglionic CB origin: dorsal motor nucleus X
Preganglionic path: CN X through the jugular foramen —> thoracic outlet —> vagal branches through the esophageal hiatus —> celiac plexus and ganglion —> to follow the postganglionic sympathetic paths
Postganglionic CB origin: intramural ganglia: Auerbach’s and Meissner’s
Postganglionic Path: direct to parasympathetic GI function
_______ provides direct input to the spleen
Sympathetic
You recall that the high threshold GVAs follow the __________ pathway, and the low threshold GVAs follow the _____________ pathway.
Sympathetic
Parasympathetic
Which of these axon types is found in the Celiac Ganglion and Plexus? CHOOSE ALL THAT APPLY!!
A. postganglionic parasympathetic
B. low threshold GVA
C.preganglionic parasympathetic
D.high threshold GVA
E. postganglionic sympathetic
B, c, d, e,
Which of these plexuses DOES NOT transmit postganglionic sympathetic axons to the stomach?
splenic
left gastric
right hepatic
right gastroepiploic
Right hepatic
All pre- to postganglionic GVE synapses use ____ that binds ____ receptors to produce fEPSP on the postganglionic cell.
A. EPI, Beta-2
B. ACh, M1
C. ACh, nicotinic cholinergic
D. NE, Beta-1
C
The parasympathetic function on sphincteric smooth muscle is via _____ binding ____ receptors.
A. ACh, M3
B. NE, alpha-1
C. ACh, M1
D. NE, beta-2
A
According to the current literature, how do parasympathetic axons influence the functioning of the spleen?
A. directly in the spleen, using ACh at M1 receptors
B. indirectly, synapsing on postganglionic sympathetic cells in the ganglia
C. they don’t influence the functioning of the spleen in any way.
D. directly in the spleen, using ACh at M3 receptors
B
Which one of these cell body types is found in the Celiac Ganglion?
A. low threshold GVA
B. postganglionic parasympathetic
C. preganglionic parasympathetic
D. high threshold GVA
E. postganglionic sympathetic
E