Molecular Biology 11 Day 13 Flashcards
(23 cards)
Name the 4 types of secretory portiens
- blood proteins
- hormones
- growth factors
- matrix that holds cells together
Nucleus to cytosol is (gated/transmembrane/vesicular) transport
gated
cytosol to : -peroxisomes -plastids -mitochondria -ER (gated/transmembrane/vesicular) transport
trans membrane
from ER to : -golgi -later endosome -secretory vesicles -lysosomes -early endosome -cell surface (gated/transmembrane/vesicular) transport
vesicular transport
pore complexes
-involved in active transport of marcomolecules and macromolecular assemblies
(free/ER bound) ribosomes make:
- cytoplasmic
- nuclear
- mitochondrial
free
(free/ER bound) ribosomes make secreted proteins
- plasma membrane protiens
- ER protiens
- golgi proteins
- lysosome protiens
ER bound
Name the 4 gated transport components
- nuclear localization sequence
- pore complexes
- import receptors
- export receptors
- P54
- P9/14
- P68/72
- binds signal sequences
P54
- P54
- P9/14
- P68/72
- required for protien translocation
P68/P72
- P54
- P9/14
- P68/72
- interact wiht ribosomes
P9/P14
- Type 1
- type 2
- Type 3
- Type 4
- cleavable signal COO- on cytosol
type 1
- Type 1
- type 2
- Type 3
- Type 4
- no cleavable signal NH3 on cytosol
type 2
- Type 1
- type 2
- Type 3
- Type 4
same as type 1 no cleavable signal
type 3
- Type 1
- type 2
- Type 3
- Type 4
- multipass
type 4
(coat recruitment GTPases/Rab proteins/SNARE protiens)
-mediate fusion with the target membrane
SNARE
(coat recruitment GTPases/Rab proteins/SNARE protiens)
-are important for regulating flow of vesicles to correct target membrane
Rab proteins
(coat recruitment GTPases/Rab proteins/SNARE protiens)
-control the assembly of clathrin COPI and COPII
coat recruitment GTPases
(phagocytosis/pinocytosis/receptormediated endocytosis)
-fusion with lysosome via phagocytic vacuole
phagotytosis
(phagocytosis/pinocytosis/receptormediated enocytosis)
-uptake of fluid droplets
pinocytosis
(phagocytosis/pinocytosis/receptormediated endocytosis)
-uptake of soluble protiens and high mol wt material
receptor mediated endocystosis
(N or O linked) -1-4 sugar residues
O linked
name the three things that makes up a oligosachharide
- NAcGLcmn-2
- Mannose
- Glucose