Monoclonal ab/biologics Flashcards

1
Q

infixumab, adalimumab, ETANERCEPT

A

TNF alpha monoclonal antibodies, 1gG1 class. Can induce apoptosis. Some not igG some igM

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2
Q

Abatacept

A

decativates t cell, targets CD80/86

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3
Q

canakinumab

A

IL-1 target

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4
Q

Tocilizumab

A

IL-6 target

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5
Q

Rituximab

A

CD20 on bcell, high risk of infection

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6
Q

tofacitinib

A

targets JAK, Decreases overactive tyrosine kinase. High risk of infection

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