Mood Disorders Flashcards Preview

Behavioral Medicine > Mood Disorders > Flashcards

Flashcards in Mood Disorders Deck (46):
1

what is mood?

pervasive and sustained tone that is internal and colors a person's behavior and perception

2

what is affect?

external manifestation of mood

3

what are mood disorders?

clinical conditions characterized by a loss of a sense of control and significant subjective distress

4

what differentiates unipolar vs bipolar?

Major depressive episodes ONLY (MDD)=unipolar
Major depressive PLUS manic episodes = bipolar

5

what is hypomania?

low grade mania sxs

6

what is cyclothymia?

low grade bipolar sxs
-lasts 2 yrs and doesn't meet criteria for bipolar I or II

7

what is dysthymia?

low grade depression sxs
-long-lasting, less severe lasting 2 yrs

8

what is unipolar mania/pure mania?

when only manic sxs are present

9

what is a major depressive episode?

distinct period of depressed mood and/or loss of interest or pleasure (must last at least 2 weeks)
-feel like they are in a fog

10

what is a manic episode?

distinct period of abn and persistently elevated, expansive and irritable mood (must last at least one week)

11

who does depression affect most?

women > men

12

who does mania affect most?

men > women

13

which gender are more rapid cyclers (4+ episodes in one year)?

women

14

what is the avg age of onset of depression?

40 yo

15

what is avg age of onset of bipolar disorder?

30 yo

16

what other things do ppl with mood disorders have an increased risk fo?

substance abuse, panic disorders, OCD, anxiety disorder (this can increase suicide risk)

17

oversupply of dopamine is a/w which disorder?

schizophrenia (also may involve glutamate)
mania

18

undersupply of serotonin is a/w which disorder?

depression
anxiety

19

what does GABA correlate with?

anxiety and intoxication

20

what is the most common condition involved in the psychiatric realm?

mood disorders

21

what is bipolar 1?

characterized by mainly manic episodes or rapid daily cycling

22

what is bipolar 2?

characterized by mainly depressive episodes accompanied by hypomania

23

which substances affect dopamine levels?

cocaine
amphetamines
ritalin
alcohol

24

which substances affect serotonin levels?

prozac
hallucinogenics (LSD)

25

what does imbalance in norepinephrine cause?

HTN, depression (undersupply)

26

which substances affect norepinephrine?

Tricyclic antidepressants
beta blockers

27

what do ACh imbalances cause?

muscular disorders
Alzheimers dz

28

which substances affect ACh levels?

nicotine
botulism toxin
curare
atropine

29

which substances affect GABA?

barbiturates
tranquilizers (valium, librium)
alcohol

30

which substances affect glutamine?

PCP

31

what anatomical changes can stress and depression cause?

HPA axis (thyroid) and changes in brain structure

32

what depressive feelings are commonly a/w suicidal thoughts?

excessive feelings of worthlessness or feelings of guilt

33

how are mood disorders inherited?

it's genetic

34

what can often trigger depressive of bipolar episodes?

significant life stressors

35

what causes future episodes of MDD or bipolar to be more likely?

changes in neurotransmission functioning in the brain

36

what is the cognitive triad of depression?

negative views of 1. self, 2. environment, 3. future

37

which PDs are more likely to also be depressed?

OCPD
histrionic
borderline

38

what is a key sxs that is common in mania?

unrestrained buying sprees (large credit card debt), sexual activity, gambling, foolish business investments

39

what is a mixed episode?

very rare
experience mania AND depression in one day

40

who has higher rates of bipolar?

higher SES (socioeconomic)

41

where is depression more common?

rural areas

42

what is the diathesis-stress model?

the idea that everyone is susceptible to some disorder

43

what is a qualifier for having an MDD recurrence?

must be 2 mo sxs free between episodes

44

how is bipolar coding differentiated?

by the manic episodes

45

what is a qualifier for having a bipolar recurrence?

must be 2 mo without a manic or hypomanic episode

46

what is a paradoxical suicide?

depressed pts actually commit suicide even when they are getting better