more qs Flashcards

(32 cards)

1
Q

2 chemo to not give with aprepitant

A

ifosphamide and etoposide

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2
Q

Mentzner index

A

MCV/rbc nymber. if <13, that. if >13, iron

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3
Q

what is APML histology

A

bilobed or folded nucleus with azurophiic granules and anger rods

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4
Q

t(6:9)

A

AML, often with FLT3

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5
Q

what probs are AML 3q with

A

megakarycotytes

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6
Q

what factors are in 4 factor activated prothrombin complex

A

2, 7, 9 and 10

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7
Q

most common secondary cancer after irradiation for solid tumor in childhood (in first 20 years)

A

osteosarcoma

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8
Q

graphical display to determine I fa change has resulted in improvement

A

run chart or trend chart

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9
Q

tool for organizing and displaying theory of improvement

A

driver diagram

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10
Q

chart that identifies areas of greatest improvement

A

Pareto

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11
Q

chart that distinguishes between special and common variations in system

A

shewhart

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12
Q

BCOR ITD- cancer and what you screen for

A

clear cell sarcoma. bone scan and MRI brain

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13
Q

stage IV wilms with incomplete lung response after 6 cycles

A

add cy/etop

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14
Q

congenital b12 def that presents with brain atrophy, hypotonia proteinuria between 1 and 5

A

ismerslund-grasbeck

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15
Q

b12 problem presenting in first year of life with failure to thrive, vominting, weakness

A

Transcobalamin II def

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16
Q

age you need to decrease dose for dactino

17
Q

inheritance: antithrombin deficiency

18
Q

3 diseases that can coinhert with dense granule deficiency

A

WAS< hermansky padlock, chediak higashi

19
Q

how to confirm LAD II

A

flow for Silly lewis x (SLEX aka CD15a) which needs fucose

20
Q

what do you look for when flowing for LAD1

21
Q

blood product for congenital protein S or C deficiency

22
Q

met common oocation- ewings

A

distal femur and pelvis

23
Q

most common location- osteosarcoma

A

distal femur, proximal tibia, proximal humerus

24
Q

which direct thrombin inhibitor needs liver metabolism and which is kdiney

A

argatroban- liver. BZival- renal

25
best test to monitor direct tthobin
APTRT
26
most common causes (1-3) for DKC
1) bone marrow failure 2) pulmonary fibrosis 3) malignancy
27
costello syndrome aka faciocutaneouskleatl syndroem- increased risk for what
RMS, bladder, and vestibular schwannoma
28
4 syndromes that increase risk for RMS
Li fraumeni, NF1, costello, BWS
29
cancer risks for someone with HyperIgM syndrome
carcinoma of liver and bile duct, and neuroectodermal tumors of liver and panreas
30
most common bacterial infection in red blood cells
yersinia (or gram -
31
what bugs grow in plt
gram +
32
antibody in IPT
GP2b/3a, usually IgG