transfusions, MDS, etc Flashcards
(15 cards)
what cells are stored in the fridge
red cells
what cells are stored at room temp
granulocytes and plt
what cells are frozen
plasma, cryo
how long do red cells last in the fridge
42 days
what is inside cryo
fibrinogen, F8, F13, vWF
most common antibody responsible for refractory thrombocytoepnia
class 1 MHC
antibody responsible for hemolytic disease of the newborn
anti AB IgG
antibody in acute hemolytic transfusion reazction
IgM
3 somatic JMML mutations
PTPN11, NRAS, KRASG
germline JMML things 2 MUTATIONS
CBL, NF1
3 genes in the MPN spectrum
JAK2, MPL, CALR
which MPN gene increases risk of progression to AML
CALR
LCH- high risk organs
bone marrow, liver, spleen and risk is risk of deathis
risk sites for LCH neurodegeneration
pituitary, mastoid, orbital sphenoid, temporal bone