Morphine Sulfate Flashcards Preview

Paramedic Drugs Set 3 - BP / Analgesia > Morphine Sulfate > Flashcards

Flashcards in Morphine Sulfate Deck (7)
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1

Classification

Narcotic, opiate agonist 

2

Mechanism of Action

  • Binds to opioid receptors
  • Capable of inducing hypotension by depression of the vasomotor centers of the brain as well as release of histamine. 
  • Reduces stimulation of sympathetic nervous system caused by the pain & anxiety of angina.
  • Reduction of sympathetic stimulation reduces heart rate, cardiac work, & myocardial O2 demand.

3

Indications

  • Moderate to severe pain
  • Chest pain associated with ACS
  • CHF
  • Pulmonary Edema

4

Contraindications

  • Respiratory depression
  • Shock
  • Known sensitivity

5

Adverse Effects

  • Respiratory depression
  • Hypotension
  • Nausea, vomiting,
  • Dizziness lightheadedness, sedation
  • Worsening of bradycardia & heart block in some pts with acute inferior wall MI
  • Seizures, cardiac arrest
  • Anaphylactoid reactions

6

Administration

  • Pain (Adult): 2-10 mg IV/IO/IM/SubQ slowly over several minutes.
  • Chest Pain associated with ACS, CHF or Pulmonary Edema (Adult): 2-10 mg IV/IO slowly over 1-5 minutes.

7

Special Considerations

  • Use with caution in hypotension, acute bronchial asthma, respiratory insufficiency, and head truama.
  • Monitor vital signs and pulse oximetry closely
  • Be prepared to support airway and ventilations
  • Treat OD with naloxone.