MPN Flashcards

(5 cards)

1
Q

CNL mutations

A

CSF3R mutations

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2
Q

Systemic Mastocytosis mutation

A

Somatic mutations of KIT Eg KIT D816V

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3
Q

Myeloid neoplasms with eosinophilia mutation

A

platelet-derived or fibroblast-growth-factor receptors (PDGFRA, PDGFRB, FGFR1), or JAK2 point mutations or translocation

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4
Q

MPN risk of thrombosis increase in…

A

Leucocytosis or erythrocytosis

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5
Q

MPN risk of bleeding increase in…

A

Thrombocytosis (AVWS)

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