MSK differential Dx Flashcards
(297 cards)
Signs and symptoms
- pain
- swelling
- decreased ROM
- bony deformity
- asymmetrical
OA
What is Ankylosing spondylitis?
Progressive inflammatory disorder that initially affects the axial skeleton
Where in the body does ankylosing spondylitis initially affect?
axial skeleton
When is the initial onset of ankylosing spondylitis?
before 40 y/o
What are commonly the first symptoms of ankylosing spondylitis?
- mid/low back pain
- morning stiffness
- sacroiliitis
What is rheumatoid arthritis?
Chronic systemic autoimmune disorder
–> Individuals produce antibodies to their own immunogloulins, such as rheumatoid factor and ACPA.
thought to have genetic etiology
Commonly characterized by periods of exacerbation and remission
When is the avg onset of RA?
40-60 y/o
Signs and symptoms
- bilateral and symmetrical synovial joint involvement
- inflammation
- weight loss
- fever
- extreme fatigue
RA
When is the onset of juvenile RA (JRA)?
before 16 y/o
remission in 75% of cases
What diagnostic tests are used to diagnose RA?
- radiographs
- increased WBCs
- increased ESR
- anemia
- increased Rheumatoid factor
What diagnosis is characterized by decalcification of bones due to vitamin D deficiency?
Osteomalacia
s/s
- severe pain
- Fx
- weakness
- deformities
What diagnosis is characterized by trigger points?
myofascial pain syndrome
What are the histological characteristics of tendinosis/tendinopathy?
- hypercellularity
- hypervascularity
- no indication of inflammatory infiltrates
- loose collagen fibers
When is surgery warranted to treat myositis ossificans?
- Only in patients with hereditary myositis ossificans
- after maturation of the lesion (6-24 months)
- when lesions mechanically interfere with joint movement or cause nerve impingement
What diagnosis is commonly referred to as reflex sympathetic dystrophy (RSD)?
CRPS
Thought to be related to trauma or precipitating event
What triggers CRPS I?
Tissue injury
Diagnosis
Dysfunction of sympathetic nervous system including pain, circulation, and vasomotor disturbances WITHOUT nerve injury
CRPS I
What is the difference between CRPS I and II?
CRPS II involves a nerve injury
What medications can be used to treat CRPS?
- antiseizure drugs
- antidepressants
- corticosteroids
- opioids
- topical drugs
What are the long term results of CRPS?
- atrophy and weakness in close proximity to affected area(s)
- skin changes
- osteoporosis
- decreased proprioception
- contractures
- pain
- ## edema
What clinical diagnostic tests are used to diagnose CRPS?
None
What is the common name for Osteitis Deformans?
Paget’s disease
What is Paget’s disease?
Metaobolic bone disease involving abnormal osteoblastic and osteoclastic activity - characterized by initial phase of excessive bone reabsorption followed by a reactive phase of excessive abnormal bone formation
What does Paget’s disease commonly result in?
- spinal stenosis
- facet arthropathy
- possible spinal Fx
New bone structure is fragile and weak. Causes painful deformities of external and internal structures