MTC week 9 Flashcards

1
Q

propionyl Coa is converted into what?

what is the enzyme required and other products required?

A

propionyl Coa is converted into what?
Answer: D-methylmalonyl Coa

what is the enzyme required and other products required?

Answer:
propionyl Coa carboxylase [with biotin] bind a HCO3- to propionyl Coa with the energy of 1 ATP

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2
Q

D-methylmalonyl Coa is converted into L-methylmalonyl Coa using which enzyme?

A

D-methylmalonyl Coa is converted into L-methylmalonyl Coa using which enzyme?

Answer: methylmalonyl Epimerase

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3
Q

L-methylmalonyl Coa is converted into Succinyl-Coa using which enzyme and coenzyme?

A

L-methylmalonyl Coa is converted into Succinyl-Coa using which enzyme and coenzyme?

Answer: methylmalonyl Coa mutase + [coenzyme B12]

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4
Q

what is the overall equation for fatty acid synthesis?

A

what is the overall equation for fatty acid synthesis?

Answer:
8 Acetyl CoA + 7 ATP + 14 NADPH

Palmitate [16C] + 7 (ADP + P) + 14 NADP+ + 6H2O + 8CoA

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5
Q

fatty acid bind to which plasma protein when it travels in the blood?

A

fatty acid bind to which plasma protein when it travels in the blood?

Answer: Albumin

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6
Q
what is the rate limiting reaction in lipogenesis?
converts \_\_\_\_\_ into \_\_\_\_\_
by addition/removal of \_\_\_\_\_
enzyme is \_\_\_\_\_
energy requires is \_\_\_\_\_
A

what is the rate limiting reaction in lipogenesis?

Answer:
the conversion: Acetyl CoA –> malonyl CoA
by addition of CO2
using enzyme Acetyl Coa Carboxylase [ and biotin]
using energy from 1 ATP

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7
Q

what enzyme adds a CoA group to fatty acid?

A

what enzyme adds a CoA group to fatty acid?

Answer: Acetyl CoA synthetase

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8
Q

______(enzyme) transports fatty acylcarnitine from the _____ into the _____.

A

___carnitine acylcarnitine translocase ___(enzyme) transports fatty acylcarnitine from the ___inner mitochondrial membrane___ into the ___mitochondria___.

Answer:
carnitine acylcarnitine translocase transfers the molecule from the inner mitochondrial membrane to the inside of the mitochondria.

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