Muscle Flashcards

1
Q

Three types of muscle

A

skeletal, smooth, and cardiac

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2
Q

Skeletal Muscle

A

Striated Voluntary (somatic nervous system) Many nuclei per cell

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3
Q

Slow Twitch

A

AKA Red Fibers High myoglobin content Primarily derive energy aerobically Contain many mitochondria

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4
Q

Fast twitch

A

AKA white fibers Less myoglobin (rely on glycolysis and fermentation to make ATP)

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5
Q

Smooth Muscle

A

Involuntary action (autonomic nervous system) Single nucleus in cell Capable of tonus Myogenic activity

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6
Q

Myogenic activity

A

Can contract without nervous system input`

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7
Q

tonus

A

a constant state of low-level contraction -may be seen in blood vessels

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8
Q

Cardiac muscle

A

Mainly uninucleated Involuntary (automatic nervous system) Striated Myogenic activity Depolarization: SA node–>AV node –>bundle of His–>Purkinje fibers

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9
Q

Sarcomere

A

Thick (myosin) and thin (actin) filaments Z-lines: end of the alphabet and the end of the sarcomere M-line: middle of the myosin filament I-band: I is a thin letter (thin filaments only) H-zone: H is a thick letter (thick filaments only) A-band: All of the thick filament (whether or not its overlapping) During contraction, all smaller except A band

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10
Q

Titin

A

a protein that acts as a spring and anchors the actin and myosin filaments together, preventing excessive stretching of the muscle

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11
Q

Myocyte

A

AKA muscle fiber Contains many myofibrils arranged in parallel. Many myocytes in parallel form a muscle

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12
Q

Sarcolemma

A

Cell membrane of a myocyte. Capable of propagating an action potential and can distribute to all sarcomeres using a system of transverse tubules.

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13
Q

Motor unit

A

The nerve terminal (end of neuron) and the group of myocytes it controls

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14
Q

Muscle contraction

A

Binding of ATP is required for releasing the myosin head from the actin filament.

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15
Q

Tropomyosin and Troponin

A

Proteins associated with actin microfilament. When action potential reaches sarcoplasmic reticulum, Ca is released–>binds to troponin–> conformational change in tropomyosin–>exposes myosin binding sites on actin

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16
Q

Twitch

A

the response of a single muscle fiber to a brief stimulus. Latent period (time between reaching threshold and onset of contraction), contraction period, and relaxation period.

17
Q

tetanus

A

When contractions become so frequent that the muscle is unable to relax. Leads to fatigue.

18
Q

Creatine Phosphate

A

created by transferring a phosphate from ATP to Creatine during times of rest: C + ATP –> ADP + CP This can be reversed during muscle use to quickly generate ATP: ADP + CP –> ATP + C

19
Q

oxyhemoglobin dissociation curve shift

A

Right shift occurs: increased CO2, H+ (lower pH), and temp