Muscle mechanics Flashcards

(41 cards)

1
Q

length-tension relationship

A

isometric muscle contraction - tension develops at initial length before contraction
initial length-tension relationship curve made by varying muscle length at rest and measure isometric tension when muscle is maximally stimulated at that length
tension depends on muscle length before it is contracted

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2
Q

optimal length

A

length at which tension development is maximal

skeletal muscle is usually near optimal

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3
Q

what bacteria causes infection tetanus

A

clostridium tetani

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4
Q

tetanus

A

uncontrollable spasms of skeletal muscles

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5
Q

how does bacteria cause muscle spasm in tetanus

A

toxin blocks inhibitory synapses in CNS - increased activity in motor nerves

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6
Q

opisthotonus

A

a state of severe hyperextension and spasticity in which an individual’s head, neck and spinal column enter into a complete “bridging” or “arching” position

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7
Q

tetanus in relation to action potential

A

muscle fibre stimulated so rapidly it cannot relax between stimuli - maximal sustained contraction

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8
Q

summation

A

stimulation closer together do not allow muscle to relax fully

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9
Q

twitches time length

A

The muscle cell twitch can have a duration of a
few hundred milliseconds and is never refractory
can be activated to contract many times before can relax

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10
Q

summation with tetanus

A

at high frequencies of activation, there is a build up of tension which, when it reaches a maximum level of tension is called complete tetanus

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11
Q

staircase phenomenom

A

When a muscle is stimulated repetitively at a frequency below that which causes summation, there is a progressive increase in the tension developed with each twitch until a maximum twitch is reached

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12
Q

classification of muscle by appearance

A

striated and unstriated

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13
Q

striated muscle

A

skeletal

cardiac

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14
Q

unstriated muscle

A

smooth muscle

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15
Q

classification of muscle by innervation

A

voluntary and involuntary

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16
Q

voluntary muscle

A

skeletal muscle

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17
Q

involuntary muscle

A

cardiac muscle

smooth muscle

18
Q

morphology of skeletal muscle

A

long cylindrical

19
Q

morphology of cardiac muscle

20
Q

morphology of smooth muscle

A

spindle or fusiform

21
Q

nuclei of skeletal muscle

A

multiple located peripherally

22
Q

nuclei of cardiac muscle

A

one or 2 located centrally

23
Q

nuclei of smooth muscle

A

one located centrally

24
Q

what muscle has no t tubules

A

smooth muscle

25
t tubules of skeletal muscle form
triad with sarcoplasmic reticulum
26
t tubules of cardiac muscle form
dyad with sarcoplasmic reticulum
27
which muscles doesn't have electrical coupling of cells
skeletal muscle
28
electrical coupling of cells of cardiac muscle
yes - with intercalated disks contain gap junction
29
electrical coupling of cells of smooth muscle
yes - gap junction
30
what is skeletal muscle regenerated with
satellite cells
31
what muscle cannot regeneration
cardiac muscle
32
what muscle requires Ca2+ for contraction
smooth muscle
33
what regulates crossbridge formation for contraction
cardiac muscle skeletal muscle Ca2+ binding to troponin
34
what nerves or receptors control contraction of skeletal muscle
motor neurons
35
what nerves or receptors control contraction of cardiac muscle
autonomic nerves | beta adrenergic agonists
36
what nerves or receptors control contraction of smooth muscle
autonomic nerves | hormones
37
2 types of smooth muscle
multiunit | visceral
38
examples of visceral smooth muscle
* Intestine * Uterus * Bladder * Ureters * Ducts of exocrine glands * Precapillary sphincters * Small blood vessels
39
examples of multiunit smooth muscle
* Cilliary muscle * Iris * Piloerector muscles * Large arteries and veins * Arteriovenous shunt vessels * Bronchial smooth muscle
40
what regulates contraction of smooth muscle
Ca 2+ -calmodulin activation of myosin kinase and | phosphorylation of myosin
41
what muscle does NOT cause summation of twitches by increased stimulus frequency
cardiac muscle