Mycology Flashcards
(21 cards)
organism assoc with pseudomembranous esophagitis
Candida
notable for developing into pseudohyphae and true hyphae when it invades tissues
Candida albicans
thermal dimorphism
mold in the cold
yeast in the heat
Nigrosin or india ink wet mount
cryptococcus neoformans
giemsa or wright stain
histoplasma capsulatum
novel, highly selective classs of semisynthetic polypeptides that inhibit important constituents of fungal cell wall
echinocandins
primary mechanism of resistance of C. albicans against azole antifungals
mutations in the 14-alpha sterol demethylase enzyme
dermatophytoses secrete the enzyme
keratinase
digests keratin (infect only superficial keratinized structure)
Trichophyton tonsurans
tinea capitis
organism which causes fungemia in premature infants on IV lipid suppplements
Malassezia furfur
spaghetti and meatballs appearance
bacon and eggs
Malassezia furfur
Tx malassezia furfur
miconazole
endemic in Ohio and Mississippi river valleys, grows in soil contaminated with bird droppings and bat guano
H. capsulatum
tansmission of H. capsulatum is via
inhalation of microconidia
Mnemonics:
Histoplasma
Histoplasma Hides within macrophages
dimorphic fungus with broad based bud
Blastomyces dermatidis
transmission of blastomyces is via
inhalation of conidia
DOC for Blastomyces
Itraconazole
if severe: ampho B
multiple buds in wheel configuration (mariner’s wheel)
Paracoccidioides brasiliensis
chronic mucocutaneous candidiasis is assoc with a lack of immune function?
T-cell function
MCC of meningoencephalitis in HIV
Cryptococcus neoformans
