Virology

Question 1

All DNA viruses are icosahedral EXCEPT

Answer 1

Poxvirus

Question 2

All enveloped viruses acquire their envelope from plasma membrane except

Answer 2

Herpes virus (from nuclear membrane)

Question 3

Mnemonics: Naked viruses

Answer 3

Give CPR and PAPP smear to NAKED hippie
Calici, Picorna, Reo, Hepevirus
Parvo, Adeno, Papilloma, Polyoma

Question 4

All viruses are haploid EXCEPT

Answer 4

retroviruses

Question 5

Mnemonics: Segmented genome

Answer 5

Bunyaviruses, Orthomyxoviruses (influenza), Arenaviruses, Reoviruses

Question 6

Mnemonics: Negative strand RNA viruses

Answer 6

Always Bring Polymerase Or Fail Replication

-Arenaviruses, Bunyaviruses, Paramyxoviruses, Orthomyxoviruses, Filoviruses, Rhabdoviruses

Question 7

Most DNA viruses have both (+) and (-) strand except

Answer 7

Parvoviruses (ss)

Question 8

All ds DNA have icosahedral symmetry EXCEPT

Answer 8

Poxvirus

Question 9

CMV receptor

Answer 9

integrins (heparan sulfate)

Question 10

EBV receptor

Answer 10

CD21

Question 11

HIV receptor

Answer 11

CD4, CXCR4, CCR5

Question 12

Parvovirus B19 receptor

Answer 12

P antigen on RBCs

Question 13

Rabies receptor

Answer 13

Nicotinic AchR

Question 14

Rhinovirus

Answer 14

ICAM-1

Question 15

Examples of Live-atenuated vaccines

Answer 15

MISSCRY

-MMR, influenza, smallpox, sabin’s polio vaccine, chickenpox, rotavirus, yellowfever

Question 16

gene E6 inhibits

Answer 16

p53

Question 17

E7 inhibits

Answer 17

Rb

Question 18

causes progressive multifocal leukoencephalopathy (PML) in patients with AIDS

Answer 18

JC Polyoma virus

Question 19

causes hemorrhagic cystitis and nephropathy in patients with solid organ (kidney) and bone marrow transplants

Answer 19

BK Polyoma virus

Question 20

Multinucleated cells in Tzanck smear

Answer 20

HSV

Question 21

Ramsay-hunt syndrome

Answer 21

VZV

Question 22

Owl’s eye nuclear inclusions

Answer 22

CMV

Question 23

DOC for CMV

Answer 23

Gancyclovir

Question 24

HHV4

Answer 24

EBV

Question 25

HHV6

Answer 25

Roseola/ Exanthem subitum/ 6th disease

Question 26

HHV8

Answer 26

Kaposi sarcoma

Question 27

Nagayama spots

Answer 27

HHV6

Question 28

Only DNA virus that replcates in the cytoplasm

Answer 28

Poxviridae

Question 29

Guarnieri bodies

Answer 29

Smallpox/ variola virus

Question 30

pinkish, papular lesions with an umbilicated center

Answer 30

Molluscum contangiosum

Question 31

Henderso paterson bodies

Answer 31

Molluscum contangiosum virus

Question 32

only DNA that produces DNA by reverse transcription with RNA as the template

Answer 32

Hep B

Question 33

All RNA viruses have ssDNA except

Answer 33

Reovirus and Rotavirus

Question 34

Mnemonics: PERCHed on a PIC

Answer 34

Poliovirus, Echovirus, Rhinovirus, Coxsackie virus, Hep A virus PICornaviridae

Question 35

MCC of nonbacterial diarrhea in adults

Answer 35

Norwalk virus (Norovirus)

Question 36

2 major antigens of influenza virus

Answer 36

hemagglutinin (H) and neuraminidase (N)

Question 37

DOC for influenza

Answer 37

Oseltamivir | Amantadine for Influenza A only

Question 38

Mnemonics: Paramyxoviruses

Answer 38

PaRaMyxoviruses | -Parainfluenza virus, RSV, Measles virus, Mumps virus

Question 39

Warthin-finkeldey bodies

Answer 39

Measles virus

Question 40

Mnemonics: mumps

Answer 40

Mumps make your parotids and testes as big as POM-poms | -parotitis, orchitis, meningitis (aseptic)

Question 41

Steeple sign xray

Answer 41

LTB (croup)

Question 42

Coronavirus receptor

Answer 42

ACE-2 receptor

Question 43

Mnemonics: Congenital Rubella Syndrome

Answer 43

``` 5Bs of Congenital rubella Bulag (cataracts) Bingi (sensorineural deafness) Bobo (mental retardation) Butas ng puso (PDA) Blueberry muffin baby ```

Question 44

5 stages of HIV infection

Answer 44

infection, window period, seroconversion, latent period, early sx, AIDS

Question 45

HAART regimen

Answer 45

2 NRTIs (zidovudine, lamivudine), protease inhibitor (indinavir)

Question 46

malignant cells with flower shaped nucleus

Answer 46

HTLV