N37/N38 Flashcards Preview

Neuro > N37/N38 > Flashcards

Flashcards in N37/N38 Deck (41)
1

cerebellar functions

equilibrium and coordination of eye movements
maintenance of posture and muscle tone
coordinating and adjusting motor movements
planning voluntary movements
learned movements

2

Cerebellar assists in movements on the _____ side of the body

ipsilateral

3

3 lobes of cerebellum

anterior, posterior, flocculonodular lobe

4

Inferior cerebellar peduncle

spinal cord and inferior olive afferents (some vestibular efferents)

5

Middle cerebellar peduncle

pontocerebellar projection afferents of contralateral pontine nuclei

6

Superior cerebellar peduncle

efferents from deep cerebellar nuclei to thalamus and red nucleus

7

3 layers of cerebellar cortex (grey matter)

molecular layer, purkinje cell layer, granular layer

8

Molecular layer has

cell-free superior layer and purkinje dendrites + granule axons + interneurons

9

Purkinje cell layer has

purkinje cells in single continuous row that project to cerebellar cortex

10

Granular cell layer

granule cells that act as interneurons to EXCITE purkinjes

11

Cerebellar medullary layer

white matter: cerebellar afferents, efferents and deep cerebellar nuclei

12

cerebellar afferents (2 types)

climbing fibers and mossy fibers

13

Climbing fibers

contralateral IO nucleus --> inferior peduncle --> purkinje cell dendrites (carrying training info of movements)

14

Mossy fibers

enter at all sites, include all other afferents, project to granule cells (carry "state" information of muscles)

15

Cerebellar efferents

Purkinje axons to deep cerebellar nuclei, deep cerebellar nuclei --> sup. peduncle --> red nucleus and VLN of the thalamus OR --> juxtarestiform body --> ipsilateral vestibular nuclei and reticular formation

16

4 deep cerebellar nuclei in white matter

fastigial nucleus, globose nucleus, emboliform nucleus, dentate nucleus

17

Mossy fibers

terminate on granule cells--> purkinje cells of molecular layer and collateral branches excite deep cerebellar nuclei (state of muscle)

18

Input to IO from

premotor and primary motor cortices and red nucleus --> IO --> contralateral purkinje cells and collateral branches excite deep cerebellar nuclei (state of muscle)

19

MF and CF to cerebellum are used for

learning and identifying patterns of activity

20

Interneurons

except granule cells, rest are inhibitory

21

Purkinje cells

inhibit deep cerebellar nuclei while collateral branches of MF and CF are excitatory

22

Spinocerebellar tracts

unconscious proprioception and touch information (limb position, joint angle, muscle tension and length)

23

Spinocerebellar tracts for LE

Dorsal and Ventral Spinocerebellar tracts (DSCT and VSCT)

24

Spinocerebellar tracts for UE

Cuneocerebellar tract and Rostral spinocerebellar tract

25

Dorsal Spinocerebellar tract receptors

touch, pressure, and proprioception --> Ia and Ib axons

26

Dorsal Spinocerebellar tract primary neuron

periphery --> medial dorsal root entry zone --> Clarke's nucleus

27

Dorsal Spinocerebellar tract secondary neuron

clarke's nucleus (C8-L2/3) --> ipsilateral DSCT--> inferior cerebellar peduncle -->vermis

28

DSCT conveys

fine coordination of posture and movement of lower limb

29

Ventral Spinocerebellar tract receptors

golgi tendon organs

30

Ventral Spinocerebellar tract primary neuron

type Ib-->DRG -> medial entry zone--> synapse on spinal border cells

31

Ventral Spinocerebellar tract secondary neuron

decussate at anterior white commissure --> VSCT --> superior cerebellar peduncle --> decussate to ipsilateral vermis

32

VSCT conveys

coordinated movement movement and posture of entire lower limb

33

Cuneocerebellar tract receptors

proprioception (muscle spindles and golgi tendon organs)

34

Cuneocerebellar tract primary neuron

Type Ia and Ia --> DRG--> medial entry zone --> fasciculus cuneatus -->synapses on cuneatus nucleus

35

Cuneocerebellar tract secondary neuron

cuneate nucleus (Clarke's nucleus homolog)-->ipsilateral cunceocerebellar tract --> inferior cerebellar peduncle --> vermis

36

Cuneocerebellar tract conveys

fine coordination of posture and movement of UE

37

Rostral Spinocerebellar Tract primary neuron

Type Ib --> DRG --> medial entry zone --> synapse on spinal gray matter

38

Rostral Spinocerebellar Tract secondary neuron

spinal gray matter --> ipsilateral rostral spinocerebellar tract--> inferior cerebellar peduncle --> vermis

39

Rostral Spinocerebellar Tract conveys

coordinated movement movement and posture of entire upper limb (VSCT of lower limb)

40

Vestibulocerebellum

flocculonodular lobe and fastigial nucleus, ipsilaterall vestibular nuclei and responds back via direct or indirect (fastigial/juxtarestiform body) modulation of vestibular function and eye movements

41

Spinocerebellum

Vermis, fastigial, globose, emboliform nuclei, ipsilateral spinal cord, ipsilateral trigeminal, and contralateral M-I, for coordination of planned movement and current position and tone