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Name/Class: NALOXONE (Narcan)/Narcotic Antagonist

Description: Naloxone is a pure narcotic antagonist that blocks the effects of both natural and synthetic narcotics and may reverse respiratory depression.

Indications: Narcotic and synthetic narcotic overdose, coma of unknown origin.

Contraindications: Hypersensitivity to the drug, non–narcotic-induced respiratory depression.

Precautions: Possible dependency (including newborns). It also has a half-life that is shorter than that of most narcotics; hence the patient may return to the overdose state.

Dosage/Route: 0.4 to 2 mg IV/IM/IN repeated/2 to 3 min as needed up to 10 mg.
Pedi: 0.01 mg IV/IM repeated/2 to 3 min as needed up to 10 mg.

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