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LABETALOL (Normodyne, Trandate)

Name/Class: LABETALOL (Normodyne, Trandate) Selective alpha and nonselective beta-adrenergic blocker, antihypertensive

Description: Blood pressure reduction without reflex tachycardia; total peripheral resistance reduced without significant alteration in cardiac output.

Indications: Moderate to sever hypertension.

Contraindications: Bronchial asthma, congestive heart failure, cardiogenic shock, second- and third-degree heart block, bradycardia

Dosage/Route: 10 mg IV push over 1-2 minutes. May repeat or double every 10 minutes to a maximum dose of 150 mg. Infusion 2-8 mg/min, titrated to supine blood pressure.



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