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PHENYTOIN (Dilantin)


Name/Class: PHENYTOIN (Dilantin)/Anticonvulsant
Description: Phenytoin is a derivative related to phenobarbital that reduces the spread of electrical discharges in the motor cortex and inhibits seizures. It also has antidysrhythmic properties that counteract the effects of digitalis.

Indications: Seizures, status epilepticus, or cardiac dysrhythmias secondary to digitalis toxicity.

Contraindications: seizures due to hypoglycemia, sinus bradycardia, heart block, and Adams-Stokes syndrome.

Precautions: Hepatic or renal impairment, alcoholism, cardiogenic shock, elderly, bradycardia, or respiratory depression.

Dosage/Route: Seizures, status epilepticus: 10 to 15 mg/kg slow IV no more than 50mg/min

Pedi: 8 to 10 mg/kg slow IV.

Dysrhythmias: 100 mg slow IV (over 5 min) to a maximum 1,000 mg.

Pedi: 3 to 5 mg/kg slow IV.

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