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Neiserria Flashcards

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1
Q

are aerobic, nonmotile, non–spore-forming, gram-negative diplococci (pairs)

A

Neisseria spp.

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2
Q

Important species of the genus Neisseria are:

A
  1. N. meningitidis,
  2. N. gonorrhoeae,
  3. N. flavescens,
  4. N. subflava,
  5. N. sicca,
  6. N. mucosa,
  7. N. lactamica
  8. N. polysacchareae
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3
Q

are the primary human pathogens of the genus Neisseria and iron growth

A

Neisseria gonorrhoeae and neisseria meningitidis

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4
Q

Humans are the only natural host and meaning “Flow of seed”; Also known as “clap” from the French word clapoir meaning “brothel”

A

gonorrhea

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5
Q

Most commonly transmitted by sexual contact

A

Neisseria gonorrhoeae

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6
Q

Primary reservoir o n gonorrhoeae

A

Asymptomatic carrie

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7
Q

Incubation period of neisseria gonorrhoear

A

2-7 days

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8
Q

Clinical presentation

A
  • most common acute urethritis in men
  • purulent discharge and dysuria
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9
Q

Site of infection in n. Gonorrhoeae

A

Most common endocervix

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10
Q

Complication of n. Gonorrhoeae

A

Inflammatory disease

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11
Q

N. Gonorrhoeae It is inhibited by

A

Sodium polyanethol sulfonate

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12
Q

non-venereal infection is in the newborn (gonococcal eye infection)

A

Ophthalmia neonatorum

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13
Q

The eyes are coated with gonococci as the baby passes down the birth canal

A

Ophthalmia neontorum

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14
Q

Ophthalmia neonatorum can result

A

Blindness

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15
Q

Specimen collection preferred to used

A

Dacron or rayon swab

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16
Q

N. Gonorrhoeae transport media used

A

Amies medium with charcoal (within 6 hours)

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17
Q

Other term of perihepatitis

A

Fitz-Hugh-Curtis Syndrome

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18
Q

Medium of Choice of n. Gonorrhoeae

A

Chocolate agar plate

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19
Q

Selective medium of n. Gonorrhoeae

A
  1. Thayer-Martin
  2. Modified Thayer-Martin
  3. Martin-Lewis
  4. New York City
  5. GC-LECT
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20
Q

inhibits gram-positive bacteria, gram-negative ​​bacteria and fungi

A

Vancomycin and colistin

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21
Q

inhibits Proteus spp.

A

Trimethoprim

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22
Q

Incubation time of n. Gonorrhoeae

A

35 degree in 3-5% CO2

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23
Q

Nongonococcal Urethritis with organisms such as

A

Chlamydia trachomatis or ureaplasma urealyticum

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24
Q

Incubation is accomplished by use of

A

CO2 incubator or candle jar white wax only

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25
CAP or Selective Agar colony morphology
small, gray to tan, translucent, and raised after 24-48 hours of incubation
26
N. Gonorrhoeae oxidase test positive result
Purple
27
traditional method for the identification of Neisseria spp.
Carbohydrate utilization
28
meaning “Flow of seed”; Also known as “clap” from the French word clapoir meaning “brothel”
gonorrhea
29
is added to neutralize the effects of SPS
Gelatin
30
Specimens are collected from genitals or other sites, such as
Rectum, pharynx, and joint fluid
31
Cell and colony Morphology of n. Gonorrhoeae
Cell: Aerobic, non-motile, non-spore forming, flat diplococci (kidney-like shape) Colony: Small, gray to tan color, Translucent, Raised colonies
32
Natural habitat of n. Gonorrhoeae
Commensals in Mucous Membrane Respiratory tract and urogenital tract
33
N. Gonorrhoeae is only fermenter in
Glucose
34
If the organism uses the particular carbohydrate what is the production
Acid production (yellow in color)
35
It is an important etiologic agent of meningitis and meningococcemia
Neisseria meningitidids
36
n. Meningitidis Can be found on the mucosal surfaces of the
Nasopharynx and oropharynx
37
Mode of transmission of n. Meningitidis
Droplet
38
Incubation period for n. Meningitidis
1-10 days
39
• Frontal headache • Stiff neck (nuchal rigidity) • Confusion • Photophobia • 10-15% mortality rate; 10-20% neurologic complications or seizures
Meningitis
40
• Frontal headache • Stiff neck (nuchal rigidity) • Confusion • Photophobia • 10-15% mortality rate; 10-20% neurologic complications or seizures
Meningitis
41
Purpura (hemorrhaging of blood into the skin and mucous membranes producing bruises) with petechial skin rash (pinpoint red spot caused by hemorrhage) • Tachycardia • Hypotension • Thrombosis • In some cases, the disease becomes fulminant and spreads rapidly, causing: - Disseminated intravascular coagulation, - Septic shock - Hemorrhage in the adrenal glands (Waterhouse-Friderichsen syndrome)
Meningococcemia
42
Collection used in N. Meningitidis
Collection: CSF aspirate, Blood aspirate, Nasopharynx aspirate/swab, joint fluid; (uncommon) sputum aspirate, urogenital swab
43
Meduim used n. Meningitidis
Sba and cap
44
Cell Morphology of n. Meningitidis
Cell: Aerobic, non-motile, non-spore forming, flat diplococci (kidney-like shape) Colony: Medium, gray, convex colonies *with green tinge when in SBA*
45
Antibiotic for Meningitis
Penicillin
46
Antibiotic for meningococcemia
Third generation of cephalosporin
47
Chemoprophylaxis of n. Meningitidis
Rifampin or ciprofloxacin/azithromycin
48
Cell morphology of moraxella catarrhalis
Non-capsulated, non-motile, Assacharolytic Smooth, opaque, Grayish to White color; “Hockey Puck” appearance, “Wagon Wheel” appearance
49
Specimen collection of moraxella catarrhalis
Middle ear effusion, nasopharynx, sinus, sputum, bronchi
50
Medium used in moraxella catarrhalis
Cap and sba
51
Antibiotic for moraxella catarrhalis
Penicillin
52
Most strains can tolerate lower temperature and grow well at in moraxella catarrhalis
Lower temperatures 28 Celsius
53
“wagon-wheel” appearance in moraxella catarrhalis
Older colonies
54
• misidentified as N. gonorrhoeae • Non-glucose fermenter • Grows on SBA • Susceptible to colistin
N. cinerea
55
• yellow-pigmented Neisseria species that is asaccharolytic
N. flavescens
56
• large, very mucoid colonies (often adhere to the agar)
N. mucosa
57
• glucose, maltose and lactose fermenter • Misidentified as N. meningitidis (glucose and maltose fermenter only)
N. Lactamica
58
• produces large amounts of extracellular polysaccharide when grown in media containing 1% or 5% sucrose
N. polysaccharea
59
• dry, wrinkled, adherent, and breadcrumb-like colonies
N. sicca
60
• dry, wrinkled, adherent, and breadcrumb-like colonies
N. sicca
61
• “less yellow”
N. subflava
62
• rod-shaped
N. elongata, N. weaveri, N. bacilliformis

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