Neoplasia Flashcards
1
Q
neoplasia
A
- uncontrolled cell growth + differentiation
- > normal (excessive mitosis)
2
Q
neoplasm
A
- tumour
- abn mass
- within tissue
3
Q
benign neoplasm characteristics
A
- slow abn growth
- non invasive
- initially resembles normal cells
- encapsulated (restricts spread)
- growth may stop @ particular size
4
Q
malignant neoplasm characteristic
A
- rapid, abn growth
- cancerous
- d/t gene mutation
- undifferentiated cells
- invasive (spreads rapidy @ local site –> destroys local tissue + cells)
- growth continues (irreversible)
5
Q
basic genetic types (CA)
A
- proto-oncogenes
- tumor suppressors genes
- DNA repair genes
- oncogenes
6
Q
proto-oncogenes
A
- promote cell growth/division
- cause excessive growth when mutated (abn)
7
Q
tumor suppressor genes
A
- opposite of proto-oncogenes
- produce proteins that inhibit cell division/growth
- cause excessive growth/division when mutated (abn)
- ex. TP53 gene
8
Q
DNA repair genes
A
- correct defective DNA
- primary target in CA
9
Q
oncogenes
A
- cause malignant growth
10
Q
benign suffix
A
oma
11
Q
malignant suffix for epithelium in origin
A
carcinoma
12
Q
malignant suffix for mesenchyme in origin
A
sarcoma
